SCHEMBL12258255

SCHEMBL12258255

CC(C)(C)C/C=C/B(O)O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ARG2 P78540 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3104437 0.73
Fluoride SCHEMBL11521122 0.68 TSHR (0.33)
SCHEMBL151292 0.67
SCHEMBL14061003 0.67
SCHEMBL151293 0.67
SCHEMBL28569948 0.65 ARG2 (0.34) ARG2
SCHEMBL6973386 0.65
SCHEMBL6977352 0.63
SCHEMBL2000209 0.63
SCHEMBL21523586 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9943603-B2 Coferons and methods of making and using them CORNELL UNIVERSITY (US) 2018-04-17 US disclosed
US-20150105553-A1 COFERONS AND METHODS OF MAKING AND USING THEM NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-04-16 US disclosed
US-20150105553-A1 COFERONS AND METHODS OF MAKING AND USING THEM NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-04-16 US disclosed
US-8853185-B2 Coferons and methods of making and using them CORNELL UNIVERSITY (US) 2014-10-07 US disclosed
US-20110263688-A1 COFERONS AND METHODS OF MAKING AND USING THEM PURDUE RESEARCH FOUNDATION (US) 2011-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150105553-A1 COFERONS AND METHODS OF MAKING AND USING THEM MYOF, TNFSF11, F13B ARG2 1311/4885CA1 1300/4885CA2 1318/4885
US-20110263688-A1 COFERONS AND METHODS OF MAKING AND USING THEM MYOF, FTH1, TFRC ARG2 797/4885CA1 2185/4885CA2 2129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.