SCHEMBL12259261

SCHEMBL12259261

Cc1ccc(Oc2ccccc2C)cc1C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.60
SLC6A4 P31645 5/20 0.60
AR P10275 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.48
MEN1 O00255 1/20 0.48
NPC1 O15118 1/20 0.48
TSHR P16473 1/20 0.48
RAB9A P51151 1/20 0.48
KMT2A Q03164 1/20 0.48
KCNH2 Q12809 4/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
CYP2C19 P33261 1/20 0.47
GRIA2 P42262 1/20 0.44
ACHE P22303 3/20 0.43
BCHE P06276 2/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7690257 0.84 ALDH1A1 (0.59) HTR2ASLC6A4ARSMN1; SMN2MEN1
SCHEMBL822076 0.84 HTR2A (0.53) HTR2ASLC6A4ARKMT2AKCNH2
SCHEMBL14027207 0.83 HTR2A (0.56) HTR2ASLC6A4ARSMN1; SMN2MEN1
SCHEMBL8378010 0.82 AR (0.50) HTR2ASLC6A4ARSMN1; SMN2MEN1
SCHEMBL20084804 0.82 HTR2A (0.55) HTR2ASLC6A4ARSMN1; SMN2MEN1
SCHEMBL14396816 0.82 SLC6A4 (0.55) HTR2ASLC6A4ARKCNH2
SCHEMBL822304 0.81 DHFR (0.51) HTR2ASLC6A4ARSMN1; SMN2MEN1
SCHEMBL14306004 0.80 HTR2A (0.51) HTR2ASLC6A4SMN1; SMN2MEN1NPC1
SCHEMBL19422369 0.80 AR (0.51) HTR2ASLC6A4ARSMN1; SMN2MEN1
SCHEMBL47874 0.79 KMT2A (0.57) HTR2ASLC6A4SMN1; SMN2MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8821617-B2 Polyimide-co-polybenzoxazole copolymer, preparation method thereof, and gas separation membrane comprising the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2014-09-02 US disclosed
US-20110212402-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ITS APPLICATION ETERNAL CHEMICAL CO., LTD. (TW) 2011-09-01 US disclosed
US-20110212402-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ITS APPLICATION ETERNAL CHEMICAL CO., LTD. (TW) 2011-09-01 US disclosed
US-20110065823-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME Industry-University Cooperation Foundation, Hanyan g University (KR) 2011-03-17 US disclosed
US-20110065823-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME Industry-University Cooperation Foundation, Hanyan g University (KR) 2011-03-17 US disclosed
WO-2009107889-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-09-03 WO disclosed