Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620036 | 0.76 | CES2 (0.58) | RAB9ANPC1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL15120379 | 0.74 | CES2 (0.56) | RAB9ANPC1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL12260658 | 0.72 | NPC1 (0.53) | RAB9ANPC1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL12260644 | 0.72 | CES1 (0.53) | RAB9ANPC1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL10682751 | 0.72 | ALDH1A1 (0.66) | RAB9ANPC1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL20169790 | 0.70 | RIPK1 (0.50) | RAB9ANPC1SMN1; SMN2KMT2ACES2 | |
| SCHEMBL27583187 | 0.70 | CES2 (0.55) | RAB9ANPC1SMN1; SMN2KMT2ACES2 | |
| SCHEMBL27568385 | 0.70 | CES2 (0.50) | RAB9ANPC1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL11258270 | 0.69 | TSHR (0.52) | RAB9ANPC1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL14130698 | 0.69 | KMT2A (0.72) | RAB9ANPC1SMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022255-B2 | Process for preparing ketones from alpha-oxo carboxylates and aryl bromides | SALTIGO GMBH (DE) | 2011-09-20 | — | — | US | disclosed |
| US-20090221832-A1 | PROCESS FOR PREPARING KETONES FROM ALPHA-OXO CARBOXYLATES AND ARYL BROMIDES | SALTIGO GMBH (DE) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221832-A1 | PROCESS FOR PREPARING KETONES FROM ALPHA-OXO CARBOXYLATES AND ARYL BROMIDES | CBR1, CBR3, AKR1C3 | RAB9A 2512/4885NPC1 2979/4885SMN1; SMN2 3261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.