Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29553636 | 1.00 | AR (0.54) | ARCYP3A4SMN1; SMN2NPC1LMNA | |
| SCHEMBL8855258 | 0.75 | EP300 (0.32) | HIF1AEPAS1 | |
| SCHEMBL8855376 | 0.74 | SRD5A2 (0.35) | ARCYP3A4SMN1; SMN2LMNAHIF1A | |
| SCHEMBL29552794 | 0.73 | HIF1A (0.35) | HIF1AEPAS1GGPS1FDPS | |
| SCHEMBL15732245 | 0.71 | EP300 (0.46) | CYP3A4HIF1AEPAS1CACNA1GGGPS1 | |
| Triptophenolide SCHEMBL19236270 | 0.70 | CYP3A4 (1.00) | ARCYP3A4SMN1; SMN2NPC1LMNA | |
| Triptophenolide SCHEMBL29429178 | 0.70 | CYP3A4 (1.00) | ARCYP3A4SMN1; SMN2NPC1LMNA | |
| SCHEMBL9359538 | 0.69 | KARS1 (0.34) | CYP3A4HIF1AEPAS1GGPS1FDPS | |
| SCHEMBL9359973 | 0.68 | CYP3A4 (0.50) | CYP3A4LMNAHIF1AEPAS1CACNA1G | |
| SCHEMBL8855191 | 0.67 | KARS1 (0.53) | CYP3A4SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110218143-A1 | COMPOSITIONS AND METHODS FOR TISSUE REPAIR | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218143-A1 | COMPOSITIONS AND METHODS FOR TISSUE REPAIR | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2011-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218143-A1 | COMPOSITIONS AND METHODS FOR TISSUE REPAIR | CD68, TNNC1, MATR3 | AR 2559/4885CYP3A4 4188/4885SMN1; SMN2 727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.