Bromide

Bromide

SCHEMBL122633

O=C(C[n+]1ccsc1)c1ccccc1.[Br-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
KMT2A Q03164 7/20 0.57
MEN1 O00255 4/20 0.57
RAB9A P51151 1/20 0.57
KDM4E B2RXH2 3/20 0.53
PABPC1 P11940 2/20 0.53
ATM Q13315 1/20 0.53
RECQL P46063 1/20 0.50
GLA P06280 1/20 0.47
LMNA P02545 3/20 0.45
CYP1A2 P05177 1/20 0.45
ADRB2 P07550 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
LTA4H P09960 1/20 0.45
PLA2G2A P14555 1/20 0.45
MAPT P10636 1/20 0.44
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL7402288 1.00 ALDH1A1 (1.00) ALDH1A1KMT2AMEN1RAB9AKDM4E
Bromide SCHEMBL7402285 0.98 ALDH1A1 (0.97) ALDH1A1KMT2AMEN1RAB9AKDM4E
SCHEMBL1444452 0.98 ALDH1A1 (0.97) ALDH1A1KMT2AMEN1RAB9AKDM4E
Hydrochloric Acid SCHEMBL2776368 0.97 ALDH1A1 (0.94) ALDH1A1KMT2AMEN1RAB9AKDM4E
Bromide SCHEMBL28819589 0.97 ALDH1A1 (0.94) ALDH1A1KMT2AMEN1RAB9AKDM4E
Pyridine SCHEMBL2361689 0.91 ALDH1A1 (0.83) ALDH1A1KMT2AMEN1RAB9AKDM4E
Bromide SCHEMBL3854856 0.91 ALDH1A1 (0.83) ALDH1A1KMT2AMEN1RAB9AKDM4E
Bromide SCHEMBL3849524 0.84 ALDH1A1 (0.72) ALDH1A1KMT2AMEN1RAB9AKDM4E
Bromide SCHEMBL3847335 0.84 ALDH1A1 (0.72) ALDH1A1KMT2AMEN1RAB9AKDM4E
Bromide SCHEMBL4939883 0.84 ALDH1A1 (0.72) ALDH1A1KMT2AMEN1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1526 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685763-B2 Bone protein extraction without demineralization RENSSELAER POLYTECHNIC INSTITUTE (US) 2023-06-27 US claimed
US-11319342-B2 Bone protein extraction without demineralization RENSSELAER POLYTECHNIC INSTITUTE (US) 2022-05-03 US claimed
US-20210060060-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF LUNG EMPHYSEMA AND OTHER FORMS OF COPD EMPHYSEMA SOLUTIONS BV (NL) 2021-03-04 US claimed
EP-3737364-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF LUNG EMPHYSEMA AND OTHER FORMS OF COPD Emphysema Solutions BV (NL) 2020-11-18 EP claimed
CN-111615385-A Compositions and methods for treating emphysema and other forms of COPD 肺气肿解决方案私人有限公司 2020-09-01 CN claimed
US-20190194247-A1 BONE PROTEIN EXTRACTION WITHOUT DEMINERALIZATION RENSSELAER POLYTECHNIC INSTITUTE (US) 2019-06-27 US claimed
CN-105754993-B A kind of DNA extraction method for seasoned wood 中国林业科学研究院木材工业研究所 2018-06-29 CN claimed
US-20170369526-A1 BONE PROTEIN EXTRACTION WITHOUT DEMINERALIZATION RENSSELAER POLYTECHNIC INSTITUTE (US) 2017-12-28 US claimed
US-20160280764-A1 Glycation Cross-link Breakers to Increase Resistance to Enzymatic Degradation NEW YORK SOCIETY FOR THE RUPTURED AND CRIPPLED MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY 2016-09-29 US claimed
CN-105754993-A DNA extraction method for dried wood 中国林业科学研究院木材工业研究所 2016-07-13 CN claimed
WO-2003089601-A2 3-DEOXYGLUCOSONE AND SKIN DYNAMIS THERAPEUTICS, INC. (US) 2003-10-30 WO claimed
EP-0808163-B1 USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS ALTEON INC (US) 2003-07-23 EP claimed
EP-1061897-B1 GLYCYLGLYCINE OLEAMIDE IN DERMO-COSMETOLOGY FABRE PIERRE DERMO COSMETIQUE (FR) 2002-09-25 EP claimed
JP-2000502667-A 2000-03-07 JP claimed
US-5853703-A Preventing and reversing the formation of advanced glycosylation endproducts THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 1998-12-29 US claimed
EP-0868176-A1 AMINOGUANIDINE FOR TREATING NIDDM SMITHKLINE BEECHAM PLC (GB) 1998-10-07 EP claimed
EP-0808163-A2 USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS ALTEON, INC. (US) 1997-11-26 EP claimed
US-5656261-A USING A THIAZOLIUM COMPOUND THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 1997-08-12 US claimed
WO-1997023203-A1 AMINOGUANIDINE FOR TREATING NIDDM SMITHKLINE BEECHAM PLC (GB) 1997-07-03 WO claimed
WO-1996022095-A2 USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS ALTEON INC. (US) 1996-07-25 WO claimed