SCHEMBL12264641

SCHEMBL12264641

O=C1CNC(=O)C1c1cc2sccc2s1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.36
GAA P10253 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
TLK2 Q86UE8 1/20 0.33
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12264656 0.83 CYP17A1 (0.31)
SCHEMBL2396347 0.72 ALDH1A1 (0.42) GAAALDH1A1POLB
SCHEMBL31296983 0.65 GPR35 (0.39) GPR35GAAALDH1A1HDAC3HDAC4
SCHEMBL9535604 0.64 GPR35 (0.38) GPR35GAAALDH1A1HDAC3HDAC4
SCHEMBL12264643 0.63 GAA (0.38) GPR35GAAALDH1A1HDAC3HDAC4
SCHEMBL9414145 0.63 GPR35 (0.40) GPR35GAAALDH1A1HDAC3HDAC4
SCHEMBL9414150 0.59 GPR35 (0.37) GPR35GAAALDH1A1HDAC3HDAC4
SCHEMBL9376598 0.59 CA2 (0.52) GPR35GAAALDH1A1HDAC3HDAC4
SCHEMBL18876164 0.58
SCHEMBL5039262 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2550688-B1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME RAYNERGY TEK INC (TW) 2016-10-26 EP disclosed
WO-2011119446-A1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME POLYERA CORPORATION (US) 2011-09-29 WO disclosed
US-20110226338-A1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME RAYNERGY TEK INC. (TW) 2011-09-22 US disclosed
US-20110226338-A1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME RAYNERGY TEK INC. (TW) 2011-09-22 US disclosed