SCHEMBL2396347

SCHEMBL2396347

O=C1CNC(=O)C1c1cccs1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 6/20 0.38
MAPT P10636 5/20 0.38
HPGD P15428 3/20 0.38
GAA P10253 2/20 0.38
POLB P06746 1/20 0.38
HSD17B10 Q99714 5/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
CASP1 P29466 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
TSHR P16473 1/20 0.35
LTK P29376 1/20 0.35
CDK5 Q00535 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9379899 0.74 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL12264641 0.72 GPR35 (0.36) ALDH1A1GAAPOLB
SCHEMBL7678904 0.72 HSD17B10 (0.42) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL3985924 0.70 ALDH1A1 (0.44) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL821111 0.69 MAPT (0.43) MEN1KMT2AKDM4EMAPTGAA
Tenilsetam SCHEMBL194668 0.68 ALDH1A1 (0.42) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL31462136 0.67 ALDH1A1 (0.44) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL9380187 0.67 HDAC8 (0.41) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL1321301 0.66 HSD17B10 (0.38) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL8083470 0.66 ALDH1A1 (0.40) ALDH1A1MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6025383-A Substituted thiophene derivatives as pesticides and herbicides BAYER AKTIENGESELLSCHAFT (DE) 2000-02-15 US claimed
US-5807805-A Substituted thiophene derivatives as pesticides and herbicides BAYER AKTIENGESELLSCHAFT (DE) 1998-09-15 US claimed
EP-2550688-B1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME RAYNERGY TEK INC (TW) 2016-10-26 EP disclosed
EP-2550688-B1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME RAYNERGY TEK INC (TW) 2016-10-26 EP disclosed
US-8598448-B2 Pyrrolo[3,2-B]pyrrole semiconducting compounds and devices incorporating same POLYERA CORPORATION (US) 2013-12-03 US disclosed
EP-2550688-A1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME Polyera Corporation (US) 2013-01-30 EP disclosed
WO-2011119446-A1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME POLYERA CORPORATION (US) 2011-09-29 WO disclosed
WO-2011119446-A1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME POLYERA CORPORATION (US) 2011-09-29 WO disclosed
US-20110226338-A1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME RAYNERGY TEK INC. (TW) 2011-09-22 US disclosed
US-20110226338-A1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME RAYNERGY TEK INC. (TW) 2011-09-22 US disclosed
US-20110226338-A1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME RAYNERGY TEK INC. (TW) 2011-09-22 US disclosed
US-6100220-A PESTICIDES AND HERBICIDES BAYER AKTIENGESELLSCHAFT 2000-08-08 US disclosed
US-6025383-A Substituted thiophene derivatives as pesticides and herbicides BAYER AKTIENGESELLSCHAFT (DE) 2000-02-15 US disclosed
US-5807805-A Substituted thiophene derivatives as pesticides and herbicides BAYER AKTIENGESELLSCHAFT (DE) 1998-09-15 US disclosed
EP-0792272-A1 SUBSTITUTED THIOPHENE DERIVATIVES AS PESTICIDES AND HERBICIDES BAYER AG (DE) 1997-09-03 EP disclosed
WO-1996016061-A1 SUBSTITUTED THIOPHENE DERIVATIVES AS PESTICIDES AND HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-05-30 WO disclosed