Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 5/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12267662 | 0.81 | — | — | |
| SCHEMBL12267654 | 0.74 | TSHR (0.46) | TSHRLMNATYRALDH1A1HPGD | |
| SCHEMBL12267625 | 0.74 | TSHR (0.46) | TSHRLMNATYRALDH1A1HPGD | |
| SCHEMBL10002179 | 0.74 | — | — | |
| SCHEMBL13567247 | 0.69 | TSHR (0.41) | TSHRLMNATYRALDH1A1HPGD | |
| SCHEMBL10002186 | 0.69 | — | — | |
| SCHEMBL417710 | 0.68 | LPL (0.55) | TSHRCA12CA9 | |
| SCHEMBL24168797 | 0.68 | CSNK2A2 (0.36) | LMNAALDH1A1 | |
| SCHEMBL424728 | 0.65 | TSHR (0.73) | TSHRLMNATYRALDH1A1HPGD | |
| SCHEMBL12524043 | 0.64 | LIPG (0.65) | KIF11CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140037944-A1 | COVALENT ORGANIC FRAMEWORK FILMS, AND METHODS OF MAKING AND USES OF SAME | CORNELL UNIVERSITY (US) | 2014-02-06 | — | — | US | disclosed |
| US-20110230678-A1 | ORGANIC FRAMEWORK | INSILICOTECH CO., LTD (KR) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230678-A1 | ORGANIC FRAMEWORK | MCM4, DBF4, ORC3 | TSHR 4060/4885LMNA 2201/4885TYR 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.