Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | USP9X | Q93008 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21907373 | 0.86 | CHRM1 (0.56) | KMT2AALDH1A1CHRM1RAB9AMAPK1 | |
| SCHEMBL13865331 | 0.84 | CHRM1 (0.55) | KMT2AALDH1A1CHRM1RAB9AMAPK1 | |
| SCHEMBL14946445 | 0.84 | ALDH1A1 (0.55) | KMT2AALDH1A1CHRM1ALOX15HSD17B10 | |
| SCHEMBL18390251 | 0.83 | CHRM1 (0.74) | CHRM1HSD17B10RAB9AMAPK1 | |
| SCHEMBL3624311 | 0.82 | CHRM1 (0.52) | KMT2ACHRM1RAB9AMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL25272683 | 0.81 | CHRM1 (0.51) | KMT2ACHRM1RAB9AMAPK1 | |
| Hydrochloric Acid SCHEMBL25272684 | 0.81 | CHRM1 (0.51) | KMT2ACHRM1RAB9AMAPK1 | |
| SCHEMBL18390271 | 0.81 | CHRM1 (0.60) | KMT2AALDH1A1CHRM1RAB9AMAPK1 | |
| SCHEMBL4913725 | 0.80 | TSHR (0.67) | KMT2AALDH1A1ALOX15HSD17B10MEN1 | |
| SCHEMBL18713065 | 0.79 | CHRM1 (0.53) | KMT2AALDH1A1CHRM1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9609870-B2 | Herbicidal isoxazolo[5,4-b]pyridines | BASF SE (DE) | 2017-04-04 | — | — | US | disclosed |
| US-8673908-B2 | Kynurenine production inhibitor | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| US-8673908-B2 | Kynurenine production inhibitor | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20110237584-A1 | KYNURENINE PRODUCTION INHIBITOR | KYOWA KIRIN CO., LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
| US-20110237584-A1 | KYNURENINE PRODUCTION INHIBITOR | KYOWA KIRIN CO., LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
| WO-2010053182-A1 | KYNURENINE PRODUCTION INHIBITOR | 協和発酵キリン株式会社 (JP) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237584-A1 | KYNURENINE PRODUCTION INHIBITOR | KYNU, KMO, IDO1 | KMT2A 464/4885ALDH1A1 1689/4885CHRM1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.