Hypoxanthine

Hypoxanthine

SCHEMBL122844

O=c1nc[nH]c2nc[nH]c12.[NaH]

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
TP53 P04637 2/20 0.52
HPGD P15428 2/20 0.52
PTGS1 P23219 2/20 0.52
HBB P68871 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ACHE P22303 1/20 0.47
GDA Q9Y2T3 1/20 0.47
ABL1 P00519 1/20 0.42
RIN1 Q13671 1/20 0.42
ADORA2A P29274 6/20 0.42
PDE4A P27815 3/20 0.42
PDE4B Q07343 3/20 0.42
PDE4C Q08493 3/20 0.42
PDE4D Q08499 3/20 0.42
ADORA2B P29275 7/20 0.41
ADORA3 P0DMS8 6/20 0.40
XDH P47989 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hypoxanthine SCHEMBL28831842 1.00 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2TDP1TP53HPGD
Hypoxanthine SCHEMBL25383 0.98 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2TDP1TP53HPGD
Hypoxanthine SCHEMBL6673819 0.95 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2TDP1TP53HPGD
Hypoxanthine SCHEMBL560394 0.95 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2TDP1TP53HPGD
SCHEMBL6904582 0.74 ACHE (0.50) ALDH1A1SMN1; SMN2TDP1TP53HPGD
Mercaptopurine Anhydrous SCHEMBL11039488 0.71 ALDH1A1 (0.95) ALDH1A1SMN1; SMN2TDP1TP53HPGD
Water SCHEMBL9461623 0.71 ACHE (0.47) ALDH1A1SMN1; SMN2TDP1TP53HPGD
SCHEMBL30804836 0.71 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2TDP1TP53HPGD
SCHEMBL2696768 0.71 ACHE (0.42) ALDH1A1SMN1; SMN2TDP1TP53HPGD
SCHEMBL1009012 0.70 ACHE (0.50) ALDH1A1SMN1; SMN2TDP1TP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171744-A1 METHODS OF REPROGRAMMING SOMATIC CELLS AND MATERIALS RELATED THERETO CITY OF HOPE (US) 2025-05-29 US claimed
CN-116004511-B Serum-free ultralow-protein PK-15 cell culture medium and preparation method thereof 中国科学院天津工业生物技术研究所 2025-04-01 CN claimed
CN-119709597-A Serum-free culture medium and culture method for industrial production of human erythropoietin 深圳未名新鹏生物医药有限公司 2025-03-28 CN claimed
CN-119410568-A Cell nutritional composition, cell nutritional additive, method for producing virus based on host cell and method for producing vaccine 上海健士拜生物科技有限公司 2025-02-11 CN claimed
CN-119286765-A Organoid basal medium and method for maintaining and promoting organoid growth 山东伯桢生物科技有限公司 2025-01-10 CN claimed
US-20240295556-A1 METHOD FOR SIMULTANEOUSLY DIAGNOSING ERWINIA CAROTOVORA AND PHYTOPHTHORA INFESTANS IN SOIL BY USING SEMI-QUANTITATIVE LATERAL FLOW IMMUNODIAGNOSTIC TECHNIQUE VETALL LABORATORIES (KR) 2024-09-05 US claimed
CN-118497106-A Serum-free suspension culture medium capable of rapidly proliferating CHO cells 昆明学院 2024-08-16 CN claimed
CN-118222506-A Serum-free LMH cell culture medium and application thereof 上海杰威医药科技有限公司 2024-06-21 CN claimed
CN-117778299-A Serum-free culture medium for efficiently expressing recombinant collagen by CHO cells 江苏创健医疗科技股份有限公司 2024-03-29 CN claimed
CN-117683715-A Method for preparing type I NKT cells by using umbilical cord blood 博雅干细胞科技有限公司 2024-03-12 CN claimed
US-9943545-B2 Stem cell culture media and methods of enhancing cell survival FATE THERAPEUTICS, INC. (US) 2018-04-17 US claimed
US-7598083-B2 Chemically defined media compositions CENTOCOR, INC. (US) 2009-10-06 US claimed
EP-2094835-A1 PLURIPOTENT CELL GROWTH MEDIA Stem Cell Sciences (UK) Ltd (GB) 2009-09-02 EP claimed
WO-2008065381-A1 PLURIPOTENT CELL GROWTH MEDIA STEM CELL SCIENCES (UK) LTD (GB) 2008-06-05 WO claimed
US-20080124801-A1 Pluripotent cell growth media STEM CELL SCIENCES (UK) LTD. (GB) 2008-05-29 US claimed
EP-1812557-A2 CHEMICALLY DEFINED MEDIA COMPOSITIONS CENTOCOR, INC. (US) 2007-08-01 EP claimed
WO-2006050050-A2 CHEMICALLY DEFINED MEDIA COMPOSITIONS CENTOCOR, INC. (US) 2006-05-11 WO claimed
US-20060094113-A1 Chemically defined media compositions JANSSEN BIOTECH, INC. 2006-05-04 US claimed
EP-1364002-A2 PROCESS FOR THE PREPARATION OF NEUTROPHIL INHIBITORY FACTOR Pfizer Products Inc. (US) 2003-11-26 EP claimed
WO-2002016584-A2 PROCESS FOR THE PREPARATION OF NEUTROPHIL INHIBITORY FACTOR PFIZER PRODUCTS INC. (US) 2002-02-28 WO claimed