Hypoxanthine

Hypoxanthine

SCHEMBL25383

O=c1nc[nH]c2nc[nH]c12

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
TDP1 Q9NUW8 2/20 0.54
TP53 P04637 2/20 0.54
HPGD P15428 2/20 0.54
PTGS1 P23219 2/20 0.54
HBB P68871 2/20 0.54
KDM4E B2RXH2 1/20 0.54
ACHE P22303 1/20 0.48
GDA Q9Y2T3 1/20 0.48
ABL1 P00519 1/20 0.44
RIN1 Q13671 1/20 0.44
ADORA2A P29274 6/20 0.43
PDE4A P27815 3/20 0.43
PDE4B Q07343 3/20 0.43
PDE4C Q08493 3/20 0.43
PDE4D Q08499 3/20 0.43
ADORA2B P29275 7/20 0.42
ADORA3 P0DMS8 6/20 0.41
XDH P47989 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hypoxanthine SCHEMBL122844 0.98 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2TDP1TP53HPGD
Hypoxanthine SCHEMBL28831842 0.98 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2TDP1TP53HPGD
Hypoxanthine SCHEMBL6673819 0.98 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2TDP1TP53HPGD
Hypoxanthine SCHEMBL560394 0.98 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2TDP1TP53HPGD
SCHEMBL6904582 0.76 ACHE (0.50) ALDH1A1SMN1; SMN2TDP1TP53HPGD
SCHEMBL30804836 0.73 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2TDP1TP53HPGD
SCHEMBL2696768 0.73 ACHE (0.42) ALDH1A1SMN1; SMN2TDP1TP53HPGD
SCHEMBL1009012 0.72 ACHE (0.50) ALDH1A1SMN1; SMN2TDP1TP53HPGD
SCHEMBL21440777 0.71 ALDH1A1 (0.54) ALDH1A1ACHEGDAABL1RAB9A
SCHEMBL11133896 0.71 ADORA2A (0.47) ALDH1A1SMN1; SMN2TDP1TP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 147609 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146298-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
US-20260146992-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4747386-A1 DOUBLE-STRANDED OLIGONUCLEOTIDE AGENTS AND USES THEREOF Bisirna Therapeutics Pte. Ltd. (SG) 2026-05-27 EP claimed
EP-4223352-B1 DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS UROTRONIC INC (US) 2026-05-27 EP claimed
US-12637489-B2 Silicon containing modified nucleotide analogs Singular Genomics Systems, Inc. (US) 2026-05-26 US claimed
CN-122095092-A Inhibitor for inhibiting inhibin Beta E gene expression and application thereof 2026-05-26 CN claimed
CN-122081155-A Pediococcus acidilactici TC-4 capable of degrading nucleoside, purine and uric acid simultaneously and application thereof 2026-05-26 CN claimed
CN-122080194-A Anti-H5 subtype avian influenza virus hemagglutinin protein monoclonal antibody 1F8 and application thereof 2026-05-26 CN claimed
WO-1983002616-A1 COMPOSITION AND METHOD FOR FORMING A5'p5'pn3'p (AppNp) INNOVAX LAB LTD (US) 1983-08-04 WO claimed
EP-0016845-B1 METHOD AND TEST COMPOSITION FOR THE DETERMINATION OF A SUBSTRATE FOR XANTHINE-OXIDASE, INCLUDING A NOVEL XANTHINE-OXIDASE AND METHOD FOR THE PREPARATION THEREOF KYOWA HAKKO KOGYO CO., LTD. (JP) 1983-07-13 EP claimed
EP-0076647-A2 Culture media for cells originating from the immune system HANA Biologics Incorporated (US) 1983-04-13 EP claimed
US-4371613-A TRANSARABINOSYLATION USING AN ENZYME FROM BACTERIA, AN ARABINOSE DONOR AND A PURINE SOURCE AJINOMOTO COMPANY INCORPORATED (JP) 1983-02-01 US claimed
US-4341868-A PEROXIDATION; COLORIMETRY; QUANTITAVE ANALYSIS; ONE-STEP; ENTEROBACTER KYOWA HAKKO KOGYO CO., LTD. (JP) 1982-07-27 US claimed
US-4266048-A Synthesis of analogs of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1981-05-05 US claimed
EP-0016845-A1 METHOD AND TEST COMPOSITION FOR THE DETERMINATION OF A SUBSTRATE FOR XANTHINE-OXIDASE, INCLUDING A NOVEL XANTHINE-OXIDASE AND METHOD FOR THE PREPARATION THEREOF KYOWA HAKKO KOGYO CO., LTD. (JP) 1980-10-15 EP claimed
US-4218535-A Determination of enzyme substrate concentration BECKMAN INSTRUMENTS, INC. (US) 1980-08-19 US claimed
US-4108804-A Process for preparation of chromatography solid supports comprising a nucleic acid base-epoxy group containing porous gel SEITA TORU 1978-08-22 US claimed
US-3939089-A PEROXYSULFATE TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) 1976-02-17 US claimed