Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1228585 | 0.88 | FAAH (0.42) | FAAHMEN1KMT2AALDH1A1ALOX12 | |
| SCHEMBL9105880 | 0.87 | SPR (0.42) | FAAHMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27863492 | 0.86 | NPC1 (0.40) | FAAHMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL1227008 | 0.83 | FAAH (0.41) | FAAHMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5057795 | 0.83 | PPARG (0.49) | CASP3CASP7CASP8MEN1KMT2A | |
| SCHEMBL2773331 | 0.83 | CASP3 (0.47) | FAAHCASP3CASP7CASP8MEN1 | |
| Hydrochloric Acid SCHEMBL1227743 | 0.82 | FAAH (0.41) | FAAHMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29497684 | 0.82 | FAAH (0.40) | FAAHMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL18978887 | 0.82 | FAAH (0.40) | FAAHMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1884146 | 0.79 | CASP3 (0.48) | FAAHCASP3CASP7CASP8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557821-B2 | Microbiocidal heterocycles | SYNGENTA CROP PROTECTION, LLC (US) | 2013-10-15 | — | — | US | disclosed |
| CN-102596943-A | Microbiocidal heterocycles | SYNGENTA PARTICIPATIONS AG | 2012-07-18 | — | — | CN | disclosed |
| EP-2464643-A1 | MICROBIOCIDAL HETEROCYCLES | Syngenta Participations AG (CH) | 2012-06-20 | — | — | EP | disclosed |
| US-20120142700-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-06-07 | — | — | US | disclosed |
| WO-2011018401-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142700-A1 | MICROBIOCIDAL HETEROCYCLES | MPO, CYP51A1, CYP1A1 | FAAH 275/4885CASP3 355/4885CASP7 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.