SCHEMBL122869

SCHEMBL122869

CC(SC(=S)c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 2/20 0.39
CYP3A4 P08684 2/20 0.39
THPO P40225 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CHRM2 P08172 1/20 0.39
ADRA1A P35348 1/20 0.39
RGS12 O14924 1/20 0.39
GLA P06280 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
PKM P14618 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
ALOX12 P18054 1/20 0.39
NFKB1 P19838 1/20 0.39
HTR2A P28223 1/20 0.39
CYP2C19 P33261 1/20 0.39
GNAI1 P63096 1/20 0.39
MAPT P10636 3/20 0.39
ALDH1A1 P00352 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14457334 0.96 MAPT (0.39) ADRA2CCYP3A4THPOHSD17B10CHRM2
SCHEMBL16312781 0.87 CNR1 (0.41) ALDH1A1KMT2AMEN1CES2CES1
SCHEMBL16312823 0.87 MEN1 (0.42) CYP3A4CYP2D6CYP2C9ALOX15TSHR
SCHEMBL8579970 0.85 ALDH1A1 (0.40) NFKB1HTR2AMAPTALDH1A1KMT2A
SCHEMBL1524998 0.84 L3MBTL1 (0.48) CYP3A4CYP2C9PKMCYP2C19MAPT
SCHEMBL11443376 0.83 ADRA2C (0.40) ADRA2CCYP3A4THPOHSD17B10CHRM2
SCHEMBL6535241 0.83 ADRA2C (0.40) ADRA2CCYP3A4THPOHSD17B10CHRM2
SCHEMBL12590975 0.81 ADRA2C (0.39) ADRA2CCYP3A4THPOHSD17B10CHRM2
SCHEMBL14108292 0.81 MAPT (0.44) CYP3A4CYP2D6ALOX12MAPTALDH1A1
SCHEMBL17998686 0.80 ALDH1A1 (0.43) TSHRNFKB1MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023099310-A1 PREPARATION OF HIGH SOLID CONTENT, SURFACTANT-FREE LATEX USING FUNCTIONAL AMPHIPHILIC WATERBORNE MACRO-RAFT AGENT BASF SE (DE) 2023-06-08 WO claimed
CN-108641053-B Thermoplastic elastomers polymerized via reversible addition-fragmentation chain transfer of triglycerides 爱荷华州立大学研究基金会有限公司 2021-04-23 CN claimed
US-10947340-B2 Poly(acrylated polyol) and method for making and using thereof as asphalt rubber modifiers, adhesives, fracking additives, or fracking fluids IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2021-03-16 US claimed
US-10752711-B2 Thermoplastic elastomers via reversible addition-fragmentation chain transfer polymerization of triglycerides IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2020-08-25 US claimed
EP-3145966-B1 POLY(ACRYLATED POLYOL) AND METHOD FOR MAKING AND USING THEREOF AS ASPHALT RUBBER MODIFIERS, ADHESIVES, FRACKING ADDITIVES, OR FRACKING FLUIDS UNIV IOWA STATE RES FOUND INC (US) 2020-07-08 EP claimed
EP-3632942-A1 THERMOPLASTIC ELASTOMERS VIA REVERSIBLE ADDITION-FRAGMENTATION CHAIN TRANSFER POLYMERIZATION OF TRIGLYCERIDES Iowa State University Research Foundation, Inc. (US) 2020-04-08 EP claimed
CN-110627934-A Isotactic polypropylene with dithiobenzoic acid alpha-methylbenzyl ester as end group, and preparation method and application thereof 青岛科技大学 2019-12-31 CN claimed
US-20190300637-A1 MULTIBLOCK COPOLYMER AND METHOD OF MAKING THEREOF IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2019-10-03 US claimed
EP-2999727-B1 THERMOPLASTIC ELASTOMERS VIA REVERSIBLE ADDITION-FRAGMENTATION CHAIN TRANSFER POLYMERIZATION OF TRIGLYCERIDES UNIV IOWA STATE RES FOUND INC (US) 2019-07-10 EP claimed
US-20190177454-A1 ACRYLATED AND ACYLATED OR ACETALIZED POLYOL AS A BIOBASED SUBSTITUTE FOR HARD, RIGID THERMOPLASTIC AND THERMOSET MATERIALS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2019-06-13 US claimed
EP-1136521-B1 Process for preparing an ocular lens material having hydrophilic surface MENICON CO LTD (JP) 2007-02-21 EP claimed
EP-1383828-A4 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION BIO LAYER PTY LTD (AU) 2006-10-04 EP claimed
WO-2006004536-A1 METHOD FOR PRODUCING MOLECULARLY IMPRINTED POLYMERS UNIVERSITY OF DORTMUND INFU (DE) 2006-01-12 WO claimed
US-6858309-B2 Methods of polymerization POLYMERAT PTY. LTD. (AU) 2005-02-22 US claimed
EP-1383828-A1 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION Polymerat Pty Ltd (AU) 2004-01-28 EP claimed
US-20030088028-A1 Methods of polymerization ANTEO TECHNOLOGIES PTY LTD (AU) 2003-05-08 US claimed
US-6533415-B2 Ocular lens material having hydrophilic surface and process for preparing the same MENICON CO., LTD. (JP) 2003-03-18 US claimed
WO-2002079305-A1 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION POLYMERAT PTY LTD (AU) 2002-10-10 WO claimed
US-20010050749-A1 Ocular lens material having hydrophilic surface and process for preparing the same MENICON CO., LTD. (JP) 2001-12-13 US claimed
EP-1136521-A2 Ocular lens material having hydrophilic surface and process for preparing the same Menicon Co., Ltd. (JP) 2001-09-26 EP claimed