SCHEMBL6535241

SCHEMBL6535241

CC(SC(O)=S)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 2/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.40
ADRA2A P08913 1/20 0.40
HIF1A Q16665 1/20 0.40
KMT2A Q03164 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MIF P14174 2/20 0.38
CHRM2 P08172 1/20 0.38
ADRA1A P35348 1/20 0.38
RGS12 O14924 1/20 0.38
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
PKM P14618 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11443376 0.86 ADRA2C (0.40) ADRA2CKDM4ELMNAADRA2AHIF1A
SCHEMBL12590975 0.84 ADRA2C (0.39) ADRA2CKDM4ELMNAADRA2AHIF1A
Carbazole SCHEMBL28240491 0.84 KIF11 (0.46) KDM4ELMNAKMT2AALDH1A1HSD17B10
SCHEMBL28351657 0.83 ADRA2A (0.42) ADRA2CKDM4ELMNAADRA2AHIF1A
SCHEMBL11443377 0.83 KMT2A (0.41) ADRA2CKDM4ELMNAADRA2AHIF1A
SCHEMBL28351658 0.83 ADRA2A (0.42) ADRA2CKDM4ELMNAADRA2AHIF1A
SCHEMBL122869 0.83 ADRA2C (0.39) ADRA2CKDM4ELMNAADRA2AHIF1A
SCHEMBL16240802 0.81 PTGS2 (0.37) ADRA2CKDM4ELMNAADRA2AHIF1A
SCHEMBL5616716 0.81 ADRA2A (0.41) ADRA2CKDM4ELMNAADRA2AHIF1A
SCHEMBL18787059 0.81 ADRA2A (0.41) ADRA2CKDM4ELMNAADRA2AHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109762625-A Poly- (methyl) the acrylate brush polymer of polydialkysiloxane for lubricant additive application 雅富顿化学公司 2019-05-17 CN disclosed
CN-106459813-A Lubricant containing polymer blend 路博润公司 2017-02-22 CN disclosed
US-20040024132-A1 Polymerization process with living characteristics and polymers made therefrom COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-02-05 US disclosed