Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MARK3 | P27448 | 1/20 | 0.36 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.36 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30682458 | 1.00 | L3MBTL1 (0.51) | L3MBTL1EPHX1HTR6BRD4CREBBP | |
| SCHEMBL29169600 | 0.90 | L3MBTL1 (0.46) | L3MBTL1EPHX1HTR6BRD4CREBBP | |
| SCHEMBL11942318 | 0.89 | L3MBTL1 (0.47) | L3MBTL1EPHX1HTR6BRD4CREBBP | |
| SCHEMBL11952570 | 0.89 | L3MBTL1 (0.47) | L3MBTL1EPHX1HTR6BRD4CREBBP | |
| SCHEMBL30682530 | 0.85 | L3MBTL1 (0.49) | L3MBTL1EPHX1HTR6BRD4CREBBP | |
| SCHEMBL22154080 | 0.85 | L3MBTL1 (0.49) | L3MBTL1EPHX1HTR6BRD4CREBBP | |
| SCHEMBL30682524 | 0.85 | L3MBTL1 (0.51) | L3MBTL1EPHX1HTR6BRD4CREBBP | |
| SCHEMBL22154140 | 0.85 | L3MBTL1 (0.51) | L3MBTL1EPHX1HTR6BRD4CREBBP | |
| SCHEMBL30682532 | 0.85 | L3MBTL1 (0.51) | L3MBTL1EPHX1HTR6BRD4CREBBP | |
| SCHEMBL2315227 | 0.85 | L3MBTL1 (0.51) | L3MBTL1EPHX1HTR6BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192888-B2 | Antibacterial compounds | THE UNIVERSITY OF NOTTINGHAM (GB) | 2021-12-07 | — | — | US | disclosed |
| US-20200199118-A1 | ANTIBACTERIAL COMPOUNDS | THE UNIVERSITY OF NOTTINGHAM (GB) | 2020-06-25 | — | — | US | disclosed |
| US-20120190701-A1 | RENIN INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2012-07-26 | — | — | US | disclosed |
| EP-2467385-A1 | RENIN INHIBITORS | Merck Canada Inc. (CA) | 2012-06-27 | — | — | EP | disclosed |
| WO-2011020193-A1 | RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2011-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192888-B2 | Antibacterial compounds | CFTR, CLPP, MRPL21 | L3MBTL1 2697/4885EPHX1 4203/4885HTR6 4050/4885 |
| US-20200199118-A1 | ANTIBACTERIAL COMPOUNDS | CFTR, CLPP, MRPL21 | L3MBTL1 2697/4885EPHX1 4203/4885HTR6 4050/4885 |
| US-20120190701-A1 | RENIN INHIBITORS | REN, ACE, AGTR1 | L3MBTL1 3966/4885EPHX1 710/4885HTR6 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.