Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1227412 | 0.92 | CHRNB2 (0.34) | CHRNB2CHRNA4 | |
| SCHEMBL1229195 | 0.92 | CHRNB2 (0.34) | CHRNB2CHRNA4 | |
| SCHEMBL18990452 | 0.81 | CHRNB2 (0.39) | CHRNB2CHRNA4 | |
| SCHEMBL30152184 | 0.81 | CHRNB2 (0.39) | CHRNB2CHRNA4 | |
| SCHEMBL25401134 | 0.79 | CHRNB2 (0.38) | CHRNB2CHRNA4 | |
| SCHEMBL31637830 | 0.79 | CHRNB2 (0.38) | CHRNB2CHRNA4 | |
| SCHEMBL1227414 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL30618353 | 0.76 | AAK1 (0.41) | — | |
| SCHEMBL29790285 | 0.76 | CA12 (0.41) | CHRNB2CHRNA4 | |
| SCHEMBL1727022 | 0.76 | CA12 (0.41) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293734-B2 | Nitroimidazooxazine and nitroimidazooxazole analogues and their uses | GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) | 2012-10-23 | — | — | US | disclosed |
| US-20110028466-A1 | NITROIMIDAZOOXAZINE AND NITROIMIDAZOOXAZOLE ANALOGUES AND THEIR USES | GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028466-A1 | NITROIMIDAZOOXAZINE AND NITROIMIDAZOOXAZOLE ANALOGUES AND THEIR USES | NOX5, NQO2, SIRT5 | CHRNB2 4175/4885CHRNA4 2736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.