Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTHFD1 | P11586 | 3/20 | 0.80 |
| ▸ | DHFR | P00374 | 2/20 | 0.58 |
| ▸ | ATIC | P31939 | 3/20 | 0.56 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.54 |
| ▸ | MTHFD2 | P13995 | 3/20 | 0.49 |
| ▸ | GART | P22102 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TYMS | P04818 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | FPGS | Q05932 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levomefolic Acid SCHEMBL79586 | 0.92 | MTHFD1 (0.68) | MTHFD1DHFRATICSOSTMTHFD2 | |
| Levomefolic Acid SCHEMBL20440869 | 0.92 | MTHFD1 (0.68) | MTHFD1DHFRATICSOSTMTHFD2 | |
| Levomefolic Acid SCHEMBL16466806 | 0.92 | MTHFD1 (0.68) | MTHFD1DHFRATICSOSTMTHFD2 | |
| Levomefolic Acid SCHEMBL16490221 | 0.92 | MTHFD1 (0.68) | MTHFD1DHFRATICSOSTMTHFD2 | |
| Levomefolic Acid SCHEMBL7953180 | 0.92 | MTHFD1 (0.68) | MTHFD1DHFRATICSOSTMTHFD2 | |
| Levomefolic Acid SCHEMBL3442396 | 0.92 | MTHFD1 (0.67) | MTHFD1DHFRATICSOSTMTHFD2 | |
| SCHEMBL10928467 | 0.89 | DHFR (0.68) | MTHFD1DHFRATICSOSTMTHFD2 | |
| SCHEMBL26045337 | 0.87 | MTHFD1 (0.60) | MTHFD1DHFRATICSOSTMTHFD2 | |
| SCHEMBL25849429 | 0.87 | MTHFD1 (0.60) | MTHFD1DHFRATICSOSTMTHFD2 | |
| SCHEMBL26045357 | 0.85 | MTHFD1 (0.59) | MTHFD1DHFRATICSOSTMTHFD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022245124-A1 | NOVEL ETHENE COMPOUND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | 재단법인 대구경북첨단의료산업진흥재단 | 2022-11-24 | — | — | WO | claimed |
| CN-105457038-A | Quick release type medicine phosphatide compound and medicine composition thereof | UNIV SOUTHEAST | 2016-04-06 | — | — | CN | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| CN-104244968-A | PH20 polypeptide variants, formulations, and uses thereof | HALOZYME INC | 2014-12-24 | — | — | CN | claimed |
| CN-104127469-A | New application of olive leaf crude extract and tumor therapeutic drug combined kit thereof | SHANGHAI YUXIAN MEDICAL TECHNOLOGY CO LTD | 2014-11-05 | — | — | CN | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| CN-1923173-A | Anti-cancer drugs slow release agent comprising anticancer antibiotics and booster thereof | JINAN KANGQUAN PHARMACEUTICAL (CN) | 2007-03-07 | — | — | CN | claimed |
| CN-1857723-A | Slow released anticancer medicine preparation with both amrubicin and its synergist | KANGQUAN MEDICINE SCI TECH CO (CN) | 2006-11-08 | — | — | CN | claimed |
| CN-1634584-A | Anti-cancer medicine composition containing antimetabolite | SHANDONG LANJIN BIOENGINEERING (CN) | 2005-07-06 | — | — | CN | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| US-3983118-A | Production of N5 -methyltetrahydrohomofolic acid and related reduced derivatives of homofolic acid | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1976-09-28 | — | — | US | claimed |
| EP-3782649-B1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | ASCENDIS PHARMA AS (DK) | 2025-05-14 | — | — | EP | disclosed |
| WO-2025096952-A1 | SCAFFOLDS AND SCAFFOLD HOLDERS FOR TISSUE ENGINEERING | UNIVERSITY OF CONNECTICUT (US) | 2025-05-08 | — | — | WO | disclosed |
| US-4824850-A | DIHYDROPYRIDINE-PYRIDINIUM SALT REDOX CARRIER | UNIVERSITY OF FLORIDA (US) | 1989-04-25 | — | — | US | disclosed |
| US-4540564-A | DIHYDROPYRIDINE AND/OR PYRIDINIUM SALT REDOX CARRIER | UNIVERSITY OF FLORIDA (US) | 1985-09-10 | — | — | US | disclosed |
| US-3983118-A | Production of N5 -methyltetrahydrohomofolic acid and related reduced derivatives of homofolic acid | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1976-09-28 | — | — | US | disclosed |