Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10084747 | 0.96 | CA1 (0.58) | CA1CA2CA9LMNACYP1A2 | |
| SCHEMBL18104660 | 0.96 | CA1 (0.58) | CA1CA2CA9LMNACYP1A2 | |
| SCHEMBL20032839 | 0.89 | CA1 (0.57) | CA1CA2CA9LMNACYP1A2 | |
| SCHEMBL18121281 | 0.89 | CA1 (0.57) | CA1CA2CA9LMNACYP1A2 | |
| SCHEMBL20033553 | 0.89 | CA1 (0.57) | CA1CA2CA9LMNACYP1A2 | |
| SCHEMBL18104582 | 0.88 | CA1 (0.53) | CA1CA2CA9LMNACYP1A2 | |
| SCHEMBL18095074 | 0.88 | CA1 (0.53) | CA1CA2CA9LMNACYP1A2 | |
| SCHEMBL18121285 | 0.85 | CA2 (0.60) | CA1CA2CA9LMNACYP1A2 | |
| SCHEMBL18095080 | 0.85 | CA1 (0.52) | CA1CA2CA9LMNACYP1A2 | |
| SCHEMBL328687 | 0.84 | CA1 (0.54) | CA1CA2CA9LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11220575-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | NEKTAR THERAPEUTICS (US) | 2022-01-11 | — | — | US | disclosed |
| US-20200354518-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS (US) | 2020-11-12 | — | — | US | disclosed |
| US-10759906-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | NEKTAR THERAPEUTICS (US) | 2020-09-01 | — | — | US | disclosed |
| US-9908970-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | NEKTAR THERAPEUTICS (US) | 2018-03-06 | — | — | US | disclosed |
| US-9908970-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | NEKTAR THERAPEUTICS (US) | 2018-03-06 | — | — | US | disclosed |
| US-20170121459-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS | 2017-05-04 | — | — | US | disclosed |
| US-20170121459-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS | 2017-05-04 | — | — | US | disclosed |
| US-9579392-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | NEKTAR THERAPEUTICS (US) | 2017-02-28 | — | — | US | disclosed |
| US-9579392-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | NEKTAR THERAPEUTICS (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160144046-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS | 2016-05-26 | — | — | US | disclosed |
| US-9228053-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | NEKTAR THERAPEUTICS (US) | 2016-01-05 | — | — | US | disclosed |
| US-20130280783-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS | 2013-10-24 | — | — | US | disclosed |
| US-8492503-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | NEKTAR THERAPEUTICS (US) | 2013-07-23 | — | — | US | disclosed |
| US-20110230618-A1 | Polymeric Alpha-Hydroxy Aldehyde and Ketone Reagents and Conjugation Method | NEKTAR THERAPEUTICS (US) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11220575-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | ASPH, ALDH1A1, ADH1C | CA1 285/4885CA2 2753/4885CA9 890/4885 |
| US-20200354518-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | ASPH, ALDH1A1, ADH1C | CA1 285/4885CA2 2753/4885CA9 890/4885 |
| US-20160144046-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | ASPH, ALDH1A1, ADH1C | CA1 285/4885CA2 2753/4885CA9 890/4885 |
| US-10759906-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | ASPH, ALDH1A1, ADH1C | CA1 285/4885CA2 2753/4885CA9 890/4885 |
| US-20130280783-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | ASPH, ALDH1A1, ADH1C | CA1 285/4885CA2 2753/4885CA9 890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.