Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229066 | 1.00 | ALDH1A1 (0.33) | ALDH1A1KDM4EPKMCES2CES1 | |
| SCHEMBL5278699 | 0.86 | ALDH1A1 (0.41) | ALDH1A1KDM4EPKMHSD17B10MEN1 | |
| SCHEMBL16329447 | 0.81 | RAB9A (0.33) | ALDH1A1KDM4EPKMCES2CES1 | |
| SCHEMBL20389485 | 0.80 | CES2 (0.35) | ALDH1A1KDM4ECES2CES1HSD17B10 | |
| SCHEMBL7998148 | 0.79 | — | — | |
| SCHEMBL5081272 | 0.79 | RAB9A (0.32) | ALDH1A1KDM4EPKMRAB9A | |
| SCHEMBL5081270 | 0.79 | RAB9A (0.32) | ALDH1A1KDM4EPKMRAB9A | |
| SCHEMBL30754357 | 0.79 | CES2 (0.36) | ALDH1A1KDM4ECES2CES1HSD17B10 | |
| SCHEMBL621700 | 0.79 | CES2 (0.36) | ALDH1A1KDM4ECES2CES1HSD17B10 | |
| SCHEMBL621701 | 0.79 | CES2 (0.36) | ALDH1A1KDM4ECES2CES1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4676880-B2 | — | — | 2011-04-27 | — | — | JP | claimed |
| US-7888309-B2 | 1-Alkanoyl-substituted cyclooctenes having agrestic, natural, and floral, green, woody odor notes; preferably, 1-cyclooct-3-enylethanone, 1-cyclooct-3-enylpropan-1-one, 1-cyclooct-3-enyl-2-methylpropan-1-one; cleaning compounds; personal care; cosmetics; detergents; fabric softeners; shampoos; gels etc. | GIVAUDAN SA (CH) | 2011-02-15 | — | — | US | claimed |
| US-20090325836-A1 | Cyclooct-(EN-)YL Derivatives for Use as Fragrances | GIVAUDAN SA (CH) | 2009-12-31 | — | — | US | claimed |
| EP-1555998-B1 | CYCLOOCT-(EN-)YL DERIVATIVES FOR USE AS FRAGRANCES | GIVAUDAN SA (CH) | 2009-07-29 | — | — | EP | claimed |
| JP-2006512470-A | — | — | 2006-04-13 | — | — | JP | claimed |
| US-20060014663-A1 | Cyclooct-(en-)yl derivatives for use as fragrances | GIVAUDAN SA (CH) | 2006-01-19 | — | — | US | claimed |
| EP-1555998-A1 | CYCLOOCT-(EN-)YL DERIVATIVES FOR USE AS FRAGRANCES | Givaudan SA (CH) | 2005-07-27 | — | — | EP | claimed |
| WO-2004035017-A1 | CYCLOOCT-(EN-)YL DERIVATIVES FOR USE AS FRAGRANCES | GIVAUDAN SA (CH) | 2004-04-29 | — | — | WO | claimed |
| US-7888309-B2 | 1-Alkanoyl-substituted cyclooctenes having agrestic, natural, and floral, green, woody odor notes; preferably, 1-cyclooct-3-enylethanone, 1-cyclooct-3-enylpropan-1-one, 1-cyclooct-3-enyl-2-methylpropan-1-one; cleaning compounds; personal care; cosmetics; detergents; fabric softeners; shampoos; gels etc. | GIVAUDAN SA (CH) | 2011-02-15 | — | — | US | disclosed |
| US-20090325836-A1 | Cyclooct-(EN-)YL Derivatives for Use as Fragrances | GIVAUDAN SA (CH) | 2009-12-31 | — | — | US | disclosed |
| US-7605118-B2 | 1-cyclooct-3-enylpropan-1-one; -cyclooct-3-enylpropan-1-ol; perfume, household product, laundry product, body care product or cosmetic | GIVAUDAN SA (CH) | 2009-10-20 | — | — | US | disclosed |
| EP-1555998-B1 | CYCLOOCT-(EN-)YL DERIVATIVES FOR USE AS FRAGRANCES | GIVAUDAN SA (CH) | 2009-07-29 | — | — | EP | disclosed |
| US-20060014663-A1 | Cyclooct-(en-)yl derivatives for use as fragrances | GIVAUDAN SA (CH) | 2006-01-19 | — | — | US | disclosed |
| EP-1555998-A1 | CYCLOOCT-(EN-)YL DERIVATIVES FOR USE AS FRAGRANCES | Givaudan SA (CH) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004035017-A1 | CYCLOOCT-(EN-)YL DERIVATIVES FOR USE AS FRAGRANCES | GIVAUDAN SA (CH) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014663-A1 | Cyclooct-(en-)yl derivatives for use as fragrances | ENY2, FPR1, CNR1 | ALDH1A1 379/4885KDM4E 1111/4885PKM 3283/4885 |
| US-20090325836-A1 | Cyclooct-(EN-)YL Derivatives for Use as Fragrances | ENY2, FPR1, CNR1 | ALDH1A1 379/4885KDM4E 1111/4885PKM 3283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.