Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666312 | 1.00 | AURKA (0.58) | AURKAMAPTALDH1A1RAB9ATDP1 | |
| SCHEMBL12297882 | 0.74 | FAAH (0.54) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL14883357 | 0.69 | ALDH1A1 (0.69) | AURKAMAPTALDH1A1TDP1POLB | |
| SCHEMBL14426551 | 0.69 | PSMB8 (0.84) | AURKAMAPTALDH1A1TDP1POLB | |
| SCHEMBL10669210 | 0.68 | PPARG (0.50) | AURKAMAPTALDH1A1TDP1POLB | |
| SCHEMBL12717766 | 0.68 | PTPN1 (0.60) | AURKAMAPTALDH1A1TDP1POLB | |
| SCHEMBL28242826 | 0.63 | KMT2A (0.41) | MAPTRAB9ATDP1MEN1KMT2A | |
| SCHEMBL12177564 | 0.61 | PSMB8 (0.67) | MAPTALDH1A1RAB9ATDP1POLB | |
| SCHEMBL12177712 | 0.61 | AURKA (0.75) | AURKATDP1SMN1; SMN2HPGDMGAM | |
| SCHEMBL10668048 | 0.60 | FAAH (0.56) | MAPTALDH1A1TDP1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775677-A | ANTIALLERGNES, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | disclosed |