Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22713540 | 1.00 | TRPA1 (0.40) | TRPA1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1888233 | 1.00 | TRPA1 (0.40) | TRPA1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30360130 | 1.00 | TRPA1 (0.40) | TRPA1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25197895 | 1.00 | TRPA1 (0.40) | TRPA1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1888234 | 1.00 | TRPA1 (0.40) | TRPA1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25197894 | 1.00 | TRPA1 (0.40) | TRPA1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22158952 | 0.91 | SCN4A (0.43) | TRPA1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22158956 | 0.91 | SCN4A (0.43) | TRPA1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22158954 | 0.91 | SCN4A (0.43) | TRPA1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24017054 | 0.83 | SMN1; SMN2 (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930578-A | Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith | 细胞基因公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-114269729-B | Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith | 细胞基因公司 | 2025-01-17 | — | — | CN | disclosed |
| CN-118724867-A | Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith | 细胞基因公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-118488957-A | Spirotricyclic RIPK1 inhibitors and methods of use thereof | 默沙东有限责任公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-114957212-B | Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith | 细胞基因公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20230242980-A1 | Systems and Methods for Protecting Nucleic Acid Molecules | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-08-03 | — | — | US | disclosed |
| CN-116113436-A | Systems and methods for protecting nucleic acid molecules | 斯坦福大学托管董事会 | 2023-05-12 | — | — | CN | disclosed |
| EP-4110397-A1 | SYSTEMS AND METHODS FOR PROTECTING NUCLEIC-ACID MOLECULES | The Board of Trustees of the Leland Stanford Junior University (US) | 2023-01-04 | — | — | EP | disclosed |
| CN-114957212-A | Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith | 细胞基因公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114269729-A | Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith | 细胞基因公司 | 2022-04-01 | — | — | CN | disclosed |
| US-8906914-B2 | Ethylene diamine modulators of fatty acid hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-09 | — | — | US | disclosed |
| US-20120149696-A1 | ETHYLENE DIAMINE MODULATORS OF FATTY ACID HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2012-06-14 | — | — | US | disclosed |
| WO-2011022348-A1 | ETHYLENE DIAMINE MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2011-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149696-A1 | ETHYLENE DIAMINE MODULATORS OF FATTY ACID HYDROLASE | FAAH, FAAH2, APEH | TRPA1 1477/4885GRIN2D 803/4885GRIN3B 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.