Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8756843 | 0.83 | ADORA2A (0.53) | GAAKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9325243 | 0.80 | ADORA2A (0.50) | GAAKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7258447 | 0.80 | MEN1 (0.47) | KMT2AALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL1569200 | 0.72 | ALDH1A1 (0.54) | POLBGAAGFERNOTUMKMT2A | |
| SCHEMBL712713 | 0.70 | MAPT (0.70) | NOTUMKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2273175 | 0.70 | POLB (0.44) | POLBGAAGFERNOTUMKMT2A | |
| SCHEMBL14327666 | 0.69 | ADORA3 (0.49) | GAANOTUMKMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL712415 | 0.69 | MAPT (0.73) | NOTUMKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17459093 | 0.69 | RAB9A (0.48) | POLBGAAGFERKMT2ASMN1; SMN2 | |
| SCHEMBL21523638 | 0.67 | KMT2A (0.49) | POLBKMT2AKDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107361508-B | Custom dyeing system | 卡拉莱特有限公司 | 2020-11-03 | — | — | CN | disclosed |
| EP-2464424-A1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | L'Oréal (FR) | 2012-06-20 | — | — | EP | disclosed |
| EP-2337550-A2 | METHOD FOR CONCEALING GRAY HAIRS | Henkel AG & Co. KGaA (DE) | 2011-06-29 | — | — | EP | disclosed |
| WO-2011018483-A1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | L'OREAL (FR) | 2011-02-17 | — | — | WO | disclosed |
| WO-2010046256-A2 | METHOD FOR CONCEALING GRAY HAIRS | HENKEL AG & CO. KGAA (DE) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010034626-A2 | NOVEL DEVELOPER COMPONENTS | HENKEL AG & CO. KGAA (DE) | 2010-04-01 | — | — | WO | disclosed |
| WO-2009098257-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING AT LEAST ONE CATIONIC DIAMINO-N,N-DIHYDROPYRAZOLONE DERIVATIVE | L'OREAL (FR) | 2009-08-13 | — | — | WO | disclosed |
| EP-1137391-B1 | METHOD FOR TREATING HAIR | NOVOZYMES AS (DK) | 2004-11-03 | — | — | EP | disclosed |
| US-6572843-B1 | Combining permanent dyeing and straightening; applying to reduced hair an oxidizing enzyme (Laccase), a mediator, and a chemical oxidizing agent that produces hydrogen peroxide | NOVOZYMES, A/S (DK) | 2003-06-03 | — | — | US | disclosed |