SCHEMBL1230237

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1260200	0.86	CYP2A6 (0.38)	CYP2A6ALDH1A1KDM4ETDP1MAOA
	SCHEMBL28535824	0.85	ALDH1A1 (0.40)	CYP2A6ALDH1A1KDM4ETDP1MAOA
	SCHEMBL28527062	0.83	LMNA (0.39)	CYP2A6ALDH1A1KDM4ETDP1MAOA
	SCHEMBL28580494	0.83	LMNA (0.39)	CYP2A6ALDH1A1KDM4ETDP1MAOA
	SCHEMBL25118403	0.82	KDM4E (0.35)	CYP2A6ALDH1A1KDM4ETDP1MAOA
	SCHEMBL381447	0.80	ALDH1A1 (0.58)	CYP2A6ALDH1A1KDM4ETDP1MAOA
	SCHEMBL10602187	0.78	ALDH1A1 (0.39)	ALDH1A1KDM4ETDP1KCNK2PTPRZ1
	SCHEMBL16317228	0.77	KCNK2 (0.35)	CYP2A6ALDH1A1KDM4ETDP1KCNK2
	SCHEMBL4116757	0.77	ALDH1A1 (0.32)	CYP2A6ALDH1A1KDM4ETDP1MAOA
	SCHEMBL8941503	0.76	LMNA (0.38)	CYP2A6ALDH1A1KDM4ETDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.