Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 15/20 | 0.34 |
| ▸ | HTR2B | P41595 | 15/20 | 0.34 |
| ▸ | HTR2A | P28223 | 9/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2457242 | 1.00 | FPR2 (0.36) | FPR2PARP1HTR2CHTR2BHTR2A | |
| SCHEMBL14918285 | 0.79 | FPR2 (0.39) | FPR2PARP1HTR2CHTR2BHTR2A | |
| SCHEMBL7516937 | 0.78 | MEN1 (0.37) | FPR2 | |
| SCHEMBL20525292 | 0.73 | PARP1 (0.43) | FPR2PARP1HTR2CHTR2BKDM2B | |
| SCHEMBL2993089 | 0.73 | HSD11B1 (0.46) | — | |
| SCHEMBL22481540 | 0.70 | HSD11B1 (0.33) | PARP1 | |
| SCHEMBL15114606 | 0.70 | CHRM2 (0.39) | — | |
| SCHEMBL5900855 | 0.69 | HTR2C (0.39) | PARP1HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL29199111 | 0.69 | PARP1 (0.42) | PARP1HTR2CHTR2BHTR2ATP53 | |
| SCHEMBL13950159 | 0.69 | HTR2C (0.39) | PARP1HTR2CHTR2BHTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110224186-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2011-09-15 | — | — | US | disclosed |
| US-20110224186-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2011-09-15 | — | — | US | disclosed |
| WO-2010030810-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224186-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | MGAM, MGAM2, B2M | FPR2 196/4885PARP1 806/4885HTR2C 1803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.