Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 6/20 | 0.39 |
| ▸ | HTR2B | P41595 | 5/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077957 | 0.87 | NOS1 (0.38) | NOS3NOS1ALDH1A1 | |
| SCHEMBL9077959 | 0.87 | NOS1 (0.38) | NOS3NOS1ALDH1A1 | |
| SCHEMBL9077956 | 0.87 | NOS1 (0.38) | NOS3NOS1ALDH1A1 | |
| SCHEMBL5380207 | 0.79 | HTR2C (0.39) | FPR2HTR2CHTR2BNOS3NOS1 | |
| SCHEMBL12306396 | 0.79 | FPR2 (0.36) | FPR2HTR2CHTR2BTP53HTR2A | |
| SCHEMBL23336233 | 0.79 | FPR2 (0.39) | FPR2HTR2CHTR2BNOS3NOS1 | |
| SCHEMBL2457242 | 0.79 | FPR2 (0.36) | FPR2HTR2CHTR2BTP53HTR2A | |
| Hydrochloric Acid SCHEMBL23297036 | 0.77 | FPR2 (0.39) | FPR2HTR2CHTR2BNOS3NOS1 | |
| SCHEMBL2598576 | 0.75 | NOS3 (0.30) | NOS3NOS1 | |
| SCHEMBL7516937 | 0.74 | MEN1 (0.37) | FPR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066869-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2013-05-10 | — | — | WO | disclosed |