Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 13/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | PRF1 | P14222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12306508 | 0.82 | ADORA1 (0.49) | PGRPDK2 | |
| SCHEMBL14462949 | 0.81 | PGR (0.39) | PGRHSD17B1HSD17B2PDE7APRKDC | |
| SCHEMBL19494826 | 0.80 | PGR (0.51) | PGRPDK2PDE7A | |
| SCHEMBL12306512 | 0.79 | HSD17B1 (0.46) | PGRHSD17B1HSD17B2PDK2PRF1 | |
| SCHEMBL17057198 | 0.78 | PGR (0.45) | PGRPDK2PDE7A | |
| SCHEMBL14340097 | 0.78 | APP (0.42) | PGRHSD17B1HSD17B2PDK2PRKDC | |
| SCHEMBL12306558 | 0.78 | HSD17B1 (0.45) | PGRHSD17B1HSD17B2PDK2 | |
| SCHEMBL12306510 | 0.77 | PGR (0.46) | PGRPDK2PDE7A | |
| SCHEMBL23767079 | 0.77 | PGR (0.49) | PGRPDK2PDE7A | |
| SCHEMBL23767222 | 0.77 | PGR (0.49) | PGRPDK2PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013160-B2 | Fluorene-based derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-8013160-B2 | Fluorene-based derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20100277063-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
| US-20100277063-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
| US-7781628-B2 | Fluorene-based derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| US-7781628-B2 | Fluorene-based derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| US-7683225-B2 | Fluorene-based derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-03-23 | — | — | US | disclosed |
| US-7683225-B2 | Fluorene-based derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-03-23 | — | — | US | disclosed |
| US-20080303433-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-12-11 | — | — | US | disclosed |
| US-20080303433-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100277063-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | LEF1, FLNA, AFF2 | PGR 2357/4885HSD17B1 2402/4885HSD17B2 2130/4885 |
| US-20080303433-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | FLNA, AFF2, LEF1 | PGR 2267/4885HSD17B1 2018/4885HSD17B2 1845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.