Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511417 | 0.74 | ALDH1A1 (0.33) | ALDH1A1PTPN1HTTCRHBPCRHR2 | |
| SCHEMBL9235508 | 0.67 | SIGMAR1 (0.47) | ALDH1A1HTT | |
| SCHEMBL9730908 | 0.65 | — | — | |
| SCHEMBL6984555 | 0.60 | — | — | |
| SCHEMBL10519639 | 0.60 | PTPN1 (0.38) | ALDH1A1PTPN1HTTCRHBPCRHR2 | |
| SCHEMBL20978652 | 0.60 | — | — | |
| SCHEMBL9091284 | 0.60 | — | — | |
| SCHEMBL658436 | 0.57 | ALDH1A1 (0.65) | ALDH1A1HTTCRHBPCRHR2 | |
| SCHEMBL126515 | 0.57 | — | — | |
| SCHEMBL18957266 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504906-A | Gelmethylpyrimidine intermediate compound | 山东新时代药业有限公司 | 2022-12-23 | — | — | CN | disclosed |
| EP-1842847-B1 | PROCESS FOR PRODUCTION OF 5-CHLORO-2,4-DIHYDROXYPYRIDINE | TAIHO PHARMACEUTICAL CO LTD (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-7557216-B2 | Process for production of 5-chloro-2,4-dihydroxypyridine | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20090043101-A1 | PROCESS FOR PRODUCTION OF 5-CHLORO-2,4-DIHYDROXYPYRIDINE | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| EP-1842847-A1 | PROCESS FOR PRODUCTION OF 5-CHLORO-2,4-DIHYDROXYPYRIDINE | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-10-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043101-A1 | PROCESS FOR PRODUCTION OF 5-CHLORO-2,4-DIHYDROXYPYRIDINE | DPYD, DDT, HPD | ALDH1A1 155/4885PTPN1 4039/4885HTT 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.