Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.47 |
| ▸ | DRD2 | P14416 | 6/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HK2 | P52789 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27468872 | 0.74 | SIGMAR1 (0.57) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8700031 | 0.70 | SIGMAR1 (0.53) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28638788 | 0.69 | ALDH1A1 (0.42) | ALDH1A1HTTMEN1MAPTMAPK1 | |
| SCHEMBL6511417 | 0.69 | ALDH1A1 (0.33) | ALDH1A1HTTMEN1MAPTKMT2A | |
| SCHEMBL123156 | 0.67 | ALDH1A1 (0.36) | ALDH1A1HTT | |
| SCHEMBL9642314 | 0.67 | BACE1 (0.46) | SIGMAR1DRD2ALDH1A1HK2HTT | |
| SCHEMBL8204988 | 0.67 | ALDH1A1 (0.44) | ALDH1A1HK2HTTMDM2MEN1 | |
| SCHEMBL8404008 | 0.65 | ALDH1A1 (0.39) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL23780252 | 0.64 | BACE1 (0.39) | SIGMAR1DRD2ALDH1A1HK2HTT | |
| SCHEMBL31217575 | 0.63 | MEN1 (0.42) | SIGMAR1ALDH1A1HTTMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436224-A | Plant growth regulators | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1995-07-25 | — | — | US | disclosed |