SCHEMBL12316964

SCHEMBL12316964

COc1ccc(Nc2nc(Nc3cccc(C)c3)nc(Nc3ccccc3C)n2)cc1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 4/20 0.51
APP P05067 1/20 0.50
MAPT P10636 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
GAA P10253 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ALDH1A1 P00352 2/20 0.48
RAB9A P51151 2/20 0.48
TP53 P04637 2/20 0.48
NPC1 O15118 1/20 0.48
MAPK1 P28482 1/20 0.48
NFKB1 P19838 1/20 0.48
NPY5R Q15761 1/20 0.47
GALR2 O43603 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544846 0.89 MAPT (0.59) KCNH3APPMAPTMEN1KMT2A
SCHEMBL824521 0.89 MAPT (0.59) KCNH3APPMAPTMEN1KMT2A
SCHEMBL22808559 0.89 MAPT (0.59) KCNH3MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL4544860 0.88 KCNH3 (0.57) KCNH3APPMAPTMEN1KMT2A
SCHEMBL14063216 0.88 KCNH3 (0.63) KCNH3MAPTSMN1; SMN2RAB9ATP53
SCHEMBL4544838 0.88 NFKB1 (0.59) KCNH3MAPTKMT2ASMN1; SMN2RAB9A
SCHEMBL4544811 0.88 NFKB1 (0.59) KCNH3MAPTKMT2ASMN1; SMN2RAB9A
SCHEMBL4544867 0.87 MAPT (0.56) KCNH3APPMAPTMEN1KMT2A
SCHEMBL4544869 0.86 KCNH3 (0.58) KCNH3MAPTMEN1KMT2AGAA
SCHEMBL4544824 0.85 KCNH3 (0.60) KCNH3MAPTMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263195-B2 Cellulose ester film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-09-11 US disclosed
US-8263195-B2 Cellulose ester film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-09-11 US disclosed
US-20100308264-A1 CELLULOSE ESTER FILM, OPTICALLY COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308264-A1 CELLULOSE ESTER FILM, OPTICALLY COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed