SCHEMBL4544869

SCHEMBL4544869

COc1cccc(Nc2nc(Nc3ccccc3)nc(Nc3ccccc3C)n2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 1/20 0.58
GAA P10253 1/20 0.55
POLB P06746 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
HTT P42858 2/20 0.54
TSHR P16473 1/20 0.54
MAPT P10636 3/20 0.54
TP53 P04637 2/20 0.54
EGFR P00533 1/20 0.51
ABCB1 P08183 2/20 0.50
ABCG2 Q9UNQ0 2/20 0.50
SLC2A1 P11166 1/20 0.50
RAPGEF4 Q8WZA2 1/20 0.50
ABCC1 P33527 1/20 0.50
ADORA2A P29274 1/20 0.50
ADORA1 P30542 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
MAPK1 P28482 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544824 0.97 KCNH3 (0.60) KCNH3GAAPOLBMEN1KMT2A
SCHEMBL4544861 0.89 KCNH3 (0.70) KCNH3POLBMEN1KMT2AHTT
SCHEMBL4544834 0.89 KCNH3 (0.70) KCNH3POLBMEN1KMT2AHTT
SCHEMBL14116665 0.87 KCNH3 (0.50) KCNH3POLBMEN1KMT2AHTT
SCHEMBL4547555 0.87 KCNH3 (0.50) KCNH3POLBMEN1KMT2AHTT
SCHEMBL13999983 0.86 KCNH3 (0.63) KCNH3POLBMEN1KMT2AHTT
SCHEMBL12316964 0.86 KCNH3 (0.51) KCNH3GAAMEN1KMT2AMAPT
SCHEMBL12642726 0.86 TSHR (0.46) KCNH3GAAPOLBMEN1KMT2A
SCHEMBL18550734 0.85 GAA (0.63) GAAPOLBMEN1KMT2AHTT
SCHEMBL22808559 0.84 MAPT (0.59) KCNH3GAAMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9223070-B2 Optical film, polarizing plate equipped with the optical film, process for manufacture of the polarizing plate, and liquid crystal display device Konica Minolta, Inc. (JP) 2015-12-29 US disclosed
US-20150253480-A1 RETARDATION FILM, ELONGATED CIRCULARLY POLARIZING PLATE AND ORGANIC EL DISPLAY PRODUCED USING SAID RETARDATION FILM Konica Minolta, Inc. (JP) 2015-09-10 US disclosed
US-9110243-B2 Laminate film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-08-18 US disclosed
US-9103988-B2 Liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-08-11 US disclosed
US-8976325-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-03-10 US disclosed
US-8947621-B2 Liquid crystal display device comprising a front plate having a lamda/4 plate that includes a hard coat layer and method for manufacturing the same KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2015-02-03 US disclosed
US-8681295-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-03-25 US disclosed
US-20130293812-A1 OPTICAL FILM, POLARIZING PLATE EQUIPPED WITH THE OPTICAL FILM, PROCESS FOR MANUFACTURE OF THE POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE Konica Minolta, Inc. (JP) 2013-11-07 US disclosed
US-20130169897-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE WITH FRONT PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE WITH FRONT PLATE KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2013-07-04 US disclosed
US-8477273-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2013-07-02 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed