SCHEMBL4544867

SCHEMBL4544867

COc1ccc(Nc2nc(Nc3ccc(C)cc3)nc(Nc3cccc(C)c3)n2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
GAA P10253 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
APP P05067 3/20 0.56
NFKB1 P19838 1/20 0.55
KCNH3 Q9ULD8 5/20 0.55
TP53 P04637 3/20 0.51
NPC1 O15118 1/20 0.51
ALDH1A1 P00352 1/20 0.51
MAPK1 P28482 1/20 0.51
RAB9A P51151 1/20 0.51
LMNA P02545 1/20 0.51
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA9 Q16790 1/20 0.51
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544846 0.97 MAPT (0.59) MAPTMEN1KMT2ASMN1; SMN2GAA
SCHEMBL824521 0.97 MAPT (0.59) MAPTMEN1KMT2ASMN1; SMN2GAA
SCHEMBL4544841 0.89 NFKB1 (0.67) MAPTSMN1; SMN2APPNFKB1KCNH3
SCHEMBL4544781 0.89 NFKB1 (0.67) MAPTSMN1; SMN2APPNFKB1KCNH3
SCHEMBL4544832 0.88 KCNH3 (0.65) MAPTMEN1KMT2ASMN1; SMN2GAA
SCHEMBL12732285 0.88 KCNH3 (0.68) MAPTMEN1KMT2ASMN1; SMN2GAA
SCHEMBL4544853 0.87 MAPT (0.71) MAPTMEN1KMT2ASMN1; SMN2GAA
SCHEMBL12316964 0.87 KCNH3 (0.51) MAPTMEN1KMT2ASMN1; SMN2GAA
SCHEMBL4547570 0.87 ALDH1A1 (0.50) MAPTMEN1KMT2ASMN1; SMN2GAA
SCHEMBL4544822 0.86 KCNH3 (0.67) MAPTMEN1KMT2ANFKB1KCNH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9223070-B2 Optical film, polarizing plate equipped with the optical film, process for manufacture of the polarizing plate, and liquid crystal display device Konica Minolta, Inc. (JP) 2015-12-29 US disclosed
US-20150253480-A1 RETARDATION FILM, ELONGATED CIRCULARLY POLARIZING PLATE AND ORGANIC EL DISPLAY PRODUCED USING SAID RETARDATION FILM Konica Minolta, Inc. (JP) 2015-09-10 US disclosed
US-9110243-B2 Laminate film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-08-18 US disclosed
US-9103988-B2 Liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-08-11 US disclosed
US-8976325-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-03-10 US disclosed
US-8947621-B2 Liquid crystal display device comprising a front plate having a lamda/4 plate that includes a hard coat layer and method for manufacturing the same KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2015-02-03 US disclosed
US-8681295-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-03-25 US disclosed
US-20130293812-A1 OPTICAL FILM, POLARIZING PLATE EQUIPPED WITH THE OPTICAL FILM, PROCESS FOR MANUFACTURE OF THE POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE Konica Minolta, Inc. (JP) 2013-11-07 US disclosed
US-20130169897-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE WITH FRONT PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE WITH FRONT PLATE KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2013-07-04 US disclosed
US-8477273-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2013-07-02 US disclosed
US-20080213511-A1 Optical compensation film, process for producing optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-09-04 US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080198303-A1 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080192192-A1 Optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed