SCHEMBL12317586

SCHEMBL12317586

COc1ccc(N(c2ccc(OC)cc2)c2ccc(-c3cc4c(=O)oc(-c5ccc(N(c6ccc(OC)cc6)c6ccc(OC)cc6)cc5)cc4c(=O)o3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.61
▸ KDM4E B2RXH2 4/20 0.61
▸ ALDH1A1 P00352 4/20 0.61
▸ HPGD P15428 3/20 0.61
▸ SMN1; SMN2 Q16637 3/20 0.61
▸ TDP1 Q9NUW8 1/20 0.61
▸ EGFR P00533 1/20 0.57
▸ MAOB P27338 4/20 0.52
▸ NPC1 O15118 4/20 0.51
▸ RAB9A P51151 4/20 0.51
▸ TP53 P04637 3/20 0.51
▸ CYP3A4 P08684 3/20 0.51
▸ LMNA P02545 2/20 0.51
▸ THRB P10828 2/20 0.51
▸ HSD17B10 Q99714 2/20 0.51
▸ NFKB1 P19838 2/20 0.51
▸ NFKB2 Q00653 2/20 0.51
▸ RELA Q04206 2/20 0.51
▸ RXFP1 Q9HBX9 1/20 0.51
▸ KCNA5 P22460 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18624123 0.94 KDM4E (0.56) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL14667800 0.94 KDM4E (0.56) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL18638023 0.88 PARP1 (0.49) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL18624122 0.84 TNKS (0.46) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL29461394 0.77 KDM4E (0.76) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL28045622 0.76 KDM4E (1.00) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL2511345 0.74 ESR2 (0.56) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL2213226 0.74 ESR2 (0.56) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL10057657 0.74 ESR2 (0.56) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL10057769 0.74 ESR2 (0.56) MAPTKDM4EALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170092876-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLID-STATE IMAGING DEVICE, ORGANIC LIGHT-ABSORBING MATERIAL, AND ORGANIC LIGHT-ABSORBING MATERIAL INTERMEDIATE SONY CORPORATION (JP) 2017-03-30 — — US disclosed
US-20170077413-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLID-STATE IMAGING DEVICE, AND ORGANIC LIGHT-ABSORBING MATERIAL SONY CORPORATION (JP) 2017-03-16 — — US disclosed
US-9349963-B2 Photoelectric conversion element and solid-state imaging apparatus SONY CORPORATION (JP) 2016-05-24 — — US disclosed
US-20130026341-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING APPARATUS SONY CORPORATION (JP) 2013-01-31 — — US disclosed
US-8309743-B2 Compound comprising triarylamine moieties and a condensed ring moiety, and the production method thereof THE UNIVERSITY OF TOKYO (JP) 2012-11-13 — — US disclosed
US-8309743-B2 Compound comprising triarylamine moieties and a condensed ring moiety, and the production method thereof THE UNIVERSITY OF TOKYO (JP) 2012-11-13 — — US disclosed
WO-2011118148-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING APPARATUS SONY CORPORATION (JP) 2011-09-29 — — WO disclosed
US-20110077416-A1 COMPOUND COMPRISING TRIARYLAMINE MOIETIES AND A CONDENSED RING MOIETY, AND THE PRODUCTION METHOD THEREOF THE UNIVERSITY OF TOKYO (JP) 2011-03-31 — — US disclosed
US-20110077416-A1 COMPOUND COMPRISING TRIARYLAMINE MOIETIES AND A CONDENSED RING MOIETY, AND THE PRODUCTION METHOD THEREOF THE UNIVERSITY OF TOKYO (JP) 2011-03-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130026341-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING APPARATUS H1-0, H1-10, H1-3 MAPT 1844/4885KDM4E 2059/4885ALDH1A1 2673/4885
US-20170092876-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLID-STATE IMAGING DEVICE, ORGANIC LIGHT-ABSORBING MATERIAL, AND ORGANIC LIGHT-ABSORBING MATERIAL INTERMEDIATE L1CAM, ASIC1, EPN1 MAPT 1010/4885KDM4E 3821/4885ALDH1A1 10/4885
US-20110077416-A1 COMPOUND COMPRISING TRIARYLAMINE MOIETIES AND A CONDENSED RING MOIETY, AND THE PRODUCTION METHOD THEREOF TPH1, DCXR, XDH MAPT 2967/4885KDM4E 2549/4885ALDH1A1 686/4885
US-20170077413-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLID-STATE IMAGING DEVICE, AND ORGANIC LIGHT-ABSORBING MATERIAL L1CAM, SLC19A2, SLC1A2 MAPT 948/4885KDM4E 3646/4885ALDH1A1 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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