Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15059366 | 0.88 | S100A4 (0.46) | MAPTSMN1; SMN2ALDH1A1HPGDS100A4 | |
| SCHEMBL1811733 | 0.79 | RAB9A (0.49) | MAPTTDP2ALDH1A1HPGD | |
| SCHEMBL2412345 | 0.78 | ELANE (0.40) | KIF11ALDH1A1 | |
| SCHEMBL3555266 | 0.74 | PTPN1 (0.43) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2472619 | 0.73 | MAPT (0.57) | MAPTSMN1; SMN2MAOBALDH1A1HPGD | |
| SCHEMBL7153475 | 0.73 | KDM4E (0.50) | MAPTSMN1; SMN2KIF11ALDH1A1HPGD | |
| SCHEMBL15799957 | 0.72 | FTO (0.52) | MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL734522 | 0.72 | KDM4E (0.47) | MAPTSMN1; SMN2MAOBALDH1A1KDM4E | |
| Acetic Acid SCHEMBL2470427 | 0.70 | SMN1; SMN2 (0.38) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL3524389 | 0.70 | ALDH1A1 (0.44) | MAPTALDH1A1S100A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828107-B1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-28 | — | — | EP | disclosed |