Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2612436 | 0.77 | SMN1; SMN2 (0.40) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL8563508 | 0.76 | SMN1; SMN2 (0.38) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL8521462 | 0.75 | GAA (0.41) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL1231077 | 0.74 | SMN1; SMN2 (0.36) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL2612437 | 0.74 | GABBR2 (0.40) | ALDH1A1 | |
| SCHEMBL25523061 | 0.70 | ALDH1A1 (0.32) | ALDH1A1CA2HSD17B10 | |
| SCHEMBL27655340 | 0.69 | GABBR2 (0.32) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL25522686 | 0.68 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL2612423 | 0.67 | GAA (0.47) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL10135346 | 0.66 | GAA (0.56) | SMN1; SMN2ALDH1A1CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464739-B1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2016-01-13 | — | — | EP | disclosed |
| US-8859235-B2 | Methods in cell cultures, and related inventions, employing certain additives | BASF SE (DE) | 2014-10-14 | — | — | US | disclosed |
| US-20120164162-A1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2012-06-28 | — | — | US | disclosed |
| EP-2464739-A2 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2012-06-20 | — | — | EP | disclosed |
| WO-2011018472-A2 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2011-02-17 | — | — | WO | disclosed |
| US-6359148-B1 | FOR POLYMER, LUBRICANTS; HEAT, OXIDATION RESISTANCE, PHOTOSTABILITY | NESVADBA PETER (CH) | 2002-03-19 | — | — | US | disclosed |
| US-6346630-B1 | 3-Arylbenzofuranones as stabilizers | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-02-12 | — | — | US | disclosed |
| EP-0648765-B1 | Process for the production of 3-arylbenzofuranones | CIBA SC HOLDING AG (CH) | 2000-07-12 | — | — | EP | disclosed |
| EP-0644190-B1 | Benzofuran-2-ones as stabilizers | CIBA GEIGY AG (CH) | 1999-03-17 | — | — | EP | disclosed |
| US-5814692-A | PROTECTING POLYMERS AND LUBRICANTS AGAINST THERMAL, OXIDATIVE OR LIGHT-INDUCED DEGRADATION | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-09-29 | — | — | US | disclosed |
| US-5807505-A | HEAT AND OXIDATION RESISTANCE, PHOTOSTABILITY OF POLYMERS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-09-15 | — | — | US | disclosed |
| US-5773631-A | PROTECTION OF POLYMERS AND LUBRICANTS AGAINST THERMAL, OXIDATIVE OR LIGHT INDUCED DEGRDATION | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |
| US-5693829-A | PROTECT AGAINST THERMAL, OXIDATIVE OR LIGHT-INDUCED DEGRADATION | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |
| US-5614572-A | Benzofuran-2-ones as stabilizers | CIBA-GEIGY CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |
| US-5607624-A | Process for the preparation of 3-arylbenzofuranones | CIBA-GEIGY CORPORATION (US) | 1997-03-04 | — | — | US | disclosed |
| US-5516920-A | POLYMER STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0648765-A1 | Process for the production of 3-arylbenzofuranones | CIBA-GEIGY AG (CH) | 1995-04-19 | — | — | EP | disclosed |
| EP-0644190-A1 | Benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1995-03-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120164162-A1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BBOX1, NEFM, NQO1 | HSPA5 1424/4885SMN1; SMN2 2481/4885CYP2C9 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.