SCHEMBL2612436

SCHEMBL2612436

Cc1cc2c(c(C(C)(C)C)c1)OC(=O)C2O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
ALDH1A1 P00352 1/20 0.40
CA2 P00918 1/20 0.40
POLB P06746 1/20 0.40
TYR P14679 1/20 0.40
GABBR2 O75899 1/20 0.35
GABBR1 Q9UBS5 1/20 0.35
HSPA5 P11021 1/20 0.34
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
HIF1A Q16665 2/20 0.33
CYP2D6 P10635 1/20 0.30
HSD17B10 Q99714 1/20 0.30
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466248 0.84 GABBR2 (0.48) GABBR2GABBR1PTGS1PTGS2
SCHEMBL29372618 0.84 GABBR2 (0.48) GABBR2GABBR1PTGS1PTGS2
SCHEMBL7155104 0.84
SCHEMBL7157578 0.83 GABBR2 (0.38) GABBR2GABBR1
SCHEMBL1231077 0.81 SMN1; SMN2 (0.36) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL12456266 0.80 UGT2B17 (0.36) ALDH1A1CA2PTGS1PTGS2
SCHEMBL25522686 0.77 ALDH1A1 (0.33) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL1232145 0.77 HSPA5 (0.33) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL2612423 0.76 GAA (0.47) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL10135346 0.75 GAA (0.56) SMN1; SMN2ALDH1A1CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230141533-A1 LACTONE COMPOUND FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-20230141533-A1 LACTONE COMPOUND FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-20120298007-A1 PROCESS FOR PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZATION PLATE AND DISPLAY UNIT KONICA MINOLTA OPTO, INC. (JP) 2012-11-29 US disclosed
US-20120298007-A1 PROCESS FOR PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZATION PLATE AND DISPLAY UNIT KONICA MINOLTA OPTO, INC. (JP) 2012-11-29 US disclosed
US-8274625-B2 Cellulose ester film, method for production of cellulose ester film, and protective film for polarizing plate, polarizing plate and liquid crystal display device each using the cellulose ester film KONICA MINOLTA OPTO, INC. (JP) 2012-09-25 US disclosed
US-8274625-B2 Cellulose ester film, method for production of cellulose ester film, and protective film for polarizing plate, polarizing plate and liquid crystal display device each using the cellulose ester film KONICA MINOLTA OPTO, INC. (JP) 2012-09-25 US disclosed
US-8246880-B2 Method of producing cellulose ester film, cellulose ester film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-08-21 US disclosed
US-8246737-B2 Cellulose ester optical film, polarizing plate and liquid crystal display using the same, method of manufacturing cellulose ester optical film, and copolymer KONICA MINOLTA OPTO, INC. (JP) 2012-08-21 US disclosed
US-8246737-B2 Cellulose ester optical film, polarizing plate and liquid crystal display using the same, method of manufacturing cellulose ester optical film, and copolymer KONICA MINOLTA OPTO, INC. (JP) 2012-08-21 US disclosed
US-8246880-B2 Method of producing cellulose ester film, cellulose ester film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-08-21 US disclosed
EP-0644190-B1 Benzofuran-2-ones as stabilizers CIBA GEIGY AG (CH) 1999-03-17 EP disclosed
US-5814692-A PROTECTING POLYMERS AND LUBRICANTS AGAINST THERMAL, OXIDATIVE OR LIGHT-INDUCED DEGRADATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-29 US disclosed
US-5807505-A HEAT AND OXIDATION RESISTANCE, PHOTOSTABILITY OF POLYMERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-15 US disclosed
US-5773631-A PROTECTION OF POLYMERS AND LUBRICANTS AGAINST THERMAL, OXIDATIVE OR LIGHT INDUCED DEGRDATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-06-30 US disclosed
US-5693829-A PROTECT AGAINST THERMAL, OXIDATIVE OR LIGHT-INDUCED DEGRADATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-12-02 US disclosed
US-5614572-A Benzofuran-2-ones as stabilizers CIBA-GEIGY CORPORATION (US) 1997-03-25 US disclosed
US-5607624-A Process for the preparation of 3-arylbenzofuranones CIBA-GEIGY CORPORATION (US) 1997-03-04 US disclosed
US-5516920-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1996-05-14 US disclosed
EP-0648765-A1 Process for the production of 3-arylbenzofuranones CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
EP-0644190-A1 Benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1995-03-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230141533-A1 LACTONE COMPOUND MRPS22, YWHAZ, RPLP1 SMN1; SMN2 3759/4885ALDH1A1 1317/4885CA2 1465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.