SCHEMBL12322166

SCHEMBL12322166

CCc1oc(C)nc1C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14407044 0.86 ELANE (0.31)
SCHEMBL6982153 0.73 HTT (0.32) FBP1
SCHEMBL961927 0.72
SCHEMBL25805739 0.71 FBP1 (0.39) FBP1
SCHEMBL12281631 0.68 FBP1 (0.34) FBP1
SCHEMBL12806575 0.67 FBP1 (0.40) FBP1
SCHEMBL12298943 0.67
SCHEMBL29171021 0.66 KDM4E (0.47) FBP1
SCHEMBL2303949 0.64 FBP1 (0.40) FBP1
SCHEMBL16729210 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8026195-B2 Fungicidal N-cycloalkyl-carboxamide derivatives BAYER CROPSCIENCE AG (DE) 2011-09-27 US disclosed
US-7932283-B2 Fungicide N-cyclopropyl-sulfonylamide derivatives BAYER CROPSCIENCE AG (DE) 2011-04-26 US disclosed
US-20090326016-A1 FUNGICIDAL N-CYCLOALKYL-CARBOXAMIDE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2009-12-31 US disclosed
US-20090137611-A1 Fungicide N-Cyclopropyl-Sulfonylamide Derivatives BAYER CROPSCIENCE AG (DE) 2009-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137611-A1 Fungicide N-Cyclopropyl-Sulfonylamide Derivatives CYP51A1, ERG28, CBR3 FBP1 322/4885
US-20090326016-A1 FUNGICIDAL N-CYCLOALKYL-CARBOXAMIDE DERIVATIVES CBR3, CBR1, CYCS FBP1 701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.