Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25805739 | 0.78 | FBP1 (0.39) | HTTTSHRFBP1 | |
| SCHEMBL12556558 | 0.77 | — | — | |
| SCHEMBL21737460 | 0.76 | HTT (0.30) | HTT | |
| SCHEMBL26066910 | 0.76 | HSP90AA1 (0.32) | HTTFBP1 | |
| SCHEMBL12281631 | 0.75 | FBP1 (0.34) | FBP1 | |
| SCHEMBL16847364 | 0.73 | HCRTR1 (0.32) | — | |
| SCHEMBL12298943 | 0.73 | — | — | |
| SCHEMBL12322166 | 0.73 | FBP1 (0.30) | FBP1 | |
| SCHEMBL26066920 | 0.72 | — | — | |
| SCHEMBL26205864 | 0.70 | HCRTR2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207207-B2 | Heterocyclic a amide derivatives useful as microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2012-06-26 | — | — | US | disclosed |
| US-8183416-B2 | Heterocyclic amide derivatives useful as microbiocides | SYNGENTA CROP PROTECTION, INC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-8183416-B2 | Heterocyclic amide derivatives useful as microbiocides | SYNGENTA CROP PROTECTION, INC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-20110224193-A1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | MERCK SHARP & DOHME CORP | 2011-09-15 | — | — | US | disclosed |
| US-20110224136-A1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | MERCK SHARP & DOHME CORP | 2011-09-15 | — | — | US | disclosed |
| US-7994093-B2 | Heterocyclocarboxamide derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2011-08-09 | — | — | US | disclosed |
| US-7994093-B2 | Heterocyclocarboxamide derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2011-08-09 | — | — | US | disclosed |
| EP-1940813-B1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-24 | — | — | EP | disclosed |
| US-20100204482-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-20100204482-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-20100204287-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-20100010063-A1 | HETEROCYCLOCARBOXAMIDE DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-20100010063-A1 | HETEROCYCLOCARBOXAMIDE DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-7598395-B2 | Tricyclic amine derivatives such as 3-Difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (9-isopropyl-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-yl)-amide; fungicides; horticulture | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-20080051446-A1 | Heterocyclocarboxamide Derivatives | SYNGENTA CROP PROTECTION, INC. | 2008-02-28 | — | — | US | disclosed |
| WO-2007124907-A2 | HETEROCYCLYL-CARBOXYLIC ACID (BENZONORBORNENE-5-YL)AMIDE DERIVATIVES AS FUNGICIDES FOR AGROCHEMICAL USE | SYNGENTA PARTICIPATIONS AG (CH) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010063-A1 | HETEROCYCLOCARBOXAMIDE DERIVATIVES | CBR3, CBR1, NOX1 | HTT 1728/4885TSHR 1089/4885FBP1 3546/4885 |
| US-20110224136-A1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | DGAT2, DGAT1, LCAT | HTT 1111/4885TSHR 2967/4885FBP1 302/4885 |
| US-20110224193-A1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | DGAT2, DGAT1, LCAT | HTT 1023/4885TSHR 3053/4885FBP1 362/4885 |
| US-20100204482-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | CBR3, CBR1, CYP8B1 | HTT 1861/4885TSHR 1390/4885FBP1 3538/4885 |
| US-20080051446-A1 | Heterocyclocarboxamide Derivatives | CBR3, CBR1, NOX1 | HTT 1728/4885TSHR 1089/4885FBP1 3546/4885 |
| US-20100204287-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | CBR3, CBR1, CYP8B1 | HTT 1625/4885TSHR 1191/4885FBP1 3456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.