Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.52 |
| ▸ | SNCA | P37840 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | QDPR | P09417 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25421101 | 0.82 | APP (0.52) | APPALOX5SNCAMAPTQDPR | |
| SCHEMBL338028 | 0.78 | APP (1.00) | APPALOX5SNCAMAPTQDPR | |
| SCHEMBL29006508 | 0.77 | SENP1 (0.52) | ALOX5MAPT | |
| SCHEMBL28349505 | 0.75 | APP (0.68) | APPALOX5SNCAMAPTMGAM | |
| SCHEMBL25422996 | 0.75 | APP (0.54) | APPALOX5SNCAMAPTQDPR | |
| SCHEMBL12855742 | 0.74 | ALDH1A1 (0.52) | MAPT | |
| SCHEMBL12124153 | 0.73 | ALOX5 (0.77) | APPALOX5SNCAMAPTQDPR | |
| SCHEMBL18327682 | 0.73 | ALOX5 (0.74) | APPALOX5SNCAMAPTGAA | |
| SCHEMBL25421169 | 0.73 | APP (0.52) | APPALOX5SNCAMAPTQDPR | |
| SCHEMBL12084357 | 0.73 | APP (0.88) | APPALOX5SNCAMAPTQDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1988397-B1 | COMPOSITIONS AND USES FOR STABILISING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDING | SCRIPPS RESEARCH INST (US) | 2011-09-14 | — | — | EP | disclosed |