Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | PRNP | P04156 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2431312 | 0.86 | MAPT (0.52) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL12325628 | 0.86 | MAPT (0.52) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL5023563 | 0.83 | MCL1 (0.70) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL12501358 | 0.82 | MAPK1 (0.56) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL14614991 | 0.81 | MAPT (0.49) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL8412494 | 0.80 | NPSR1 (0.74) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL693146 | 0.79 | BCKDK (0.68) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL8010924 | 0.76 | MCL1 (0.52) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL15471997 | 0.76 | BCL2L1 (0.55) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL4386528 | 0.75 | LMNA (0.69) | MAPTKDM4ELMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109679-A2 | INHIBITORS OF 5-LIPOXYGENASE | AMIRA PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |