Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17227462 | 0.88 | GHSR (0.61) | GHSRCHRM2 | |
| SCHEMBL12328016 | 0.85 | GHSR (0.59) | GHSRCHRM2 | |
| SCHEMBL2434539 | 0.84 | GHSR (0.62) | GHSRCHRM2 | |
| SCHEMBL2445065 | 0.84 | GHSR (0.57) | GHSRCHRM2 | |
| SCHEMBL2431404 | 0.79 | GHSR (0.58) | GHSRCHRM2 | |
| Hydrochloric Acid SCHEMBL2437919 | 0.78 | GHSR (0.57) | GHSRCHRM2 | |
| SCHEMBL30135908 | 0.71 | HSD17B10 (0.42) | — | |
| SCHEMBL17227458 | 0.71 | SMN1; SMN2 (0.66) | GHSRCHRM2 | |
| SCHEMBL30135848 | 0.69 | LMNA (0.39) | GHSR | |
| SCHEMBL30297575 | 0.69 | CYP3A4 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011114271-A1 | 2,3 DIHYDRO-1H-INDEN-1-YL- 2,7-DIAZASPIRO [3.6] NONANE DERIVATIVES AND THEIR USE AS ANTAGONISTS OR INVERSE AGONISTS OF THE GHRELIN RECEPTOR | PFIZER INC. (US) | 2011-09-22 | — | — | WO | disclosed |
| US-20110230461-A1 | 2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5] NONANE DERIVATIVES | PFIZER INC. | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230461-A1 | 2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5] NONANE DERIVATIVES | GIPR, GLP1R, GHSR | GHSR 3/4885CHRM2 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.