Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756817 | 1.00 | PRKCA (0.39) | PRKCAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL9756907 | 0.88 | NAAA (0.43) | PRKCAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL14430649 | 0.84 | LMNA (0.44) | PRKCAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL21143390 | 0.84 | MGAM (0.44) | PRKCAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL2854978 | 0.84 | MAPT (0.47) | KDM4EDUSP3LMNANAAAMAPT | |
| SCHEMBL30320231 | 0.84 | MAPT (0.47) | KDM4EDUSP3LMNANAAAMAPT | |
| SCHEMBL2251000 | 0.83 | LMNA (0.49) | PRKCAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL9756895 | 0.83 | LMNA (0.49) | PRKCAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL19106906 | 0.82 | MGAM (0.42) | PRKCAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL2877928 | 0.80 | ALDH1A1 (0.38) | PRKCAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316374-B1 | OPTICALLY ACTIVE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-31 | — | — | EP | claimed |
| EP-0316374-A1 | OPTICALLY ACTIVE COMPOUNDS. | HOFFMANN LA ROCHE (CH) | 1989-05-24 | — | — | EP | claimed |
| WO-1988008838-A1 | OPTICALLY ACTIVE COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1988-11-17 | — | — | WO | claimed |