Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21441726 | 0.76 | FPR2 (0.37) | ALDH1A1L3MBTL1KMT2AKDM4EGAA | |
| SCHEMBL22863835 | 0.76 | PPM1B (0.33) | PPM1B | |
| SCHEMBL6796773 | 0.76 | PPM1B (0.61) | PPM1BALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL9013023 | 0.74 | PPM1B (0.42) | PPM1BALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL19479820 | 0.72 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1KDM4EGAACYP1A2 | |
| SCHEMBL10050922 | 0.71 | — | — | |
| SCHEMBL21733026 | 0.70 | FPR3 (0.35) | ALDH1A1L3MBTL1KDM4EGAACYP1A2 | |
| SCHEMBL21133701 | 0.70 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1KDM4EGAACYP1A2 | |
| SCHEMBL19265834 | 0.68 | PPM1B (0.38) | PPM1B | |
| SCHEMBL21738139 | 0.68 | ALDH1A1 (0.37) | ALDH1A1KMT2AKDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020155017-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2020-08-06 | — | — | WO | disclosed |
| WO-2017046658-A1 | DERIVATIVES OF AMANITA TOXINS AND THEIR CONJUGATION TO A CELL BINDING MOLECULE | HANGZHOU DAC BIOTECH CO, LTD (CN) | 2017-03-23 | — | — | WO | disclosed |
| WO-2011118824-A1 | PATTERN FORMING METHOD, CHEMICAL AMPLIFICATION RESIST COMPOSITION AND RESIST FILM | FUJIFILM CORPORATION (JP) | 2011-09-29 | — | — | WO | disclosed |