SCHEMBL1233384

SCHEMBL1233384

O=C(NCC(O)CNC(=O)C(F)(F)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1234939 0.98
SCHEMBL1234198 0.80 GBA1 (0.39) CA2
SCHEMBL1233279 0.76
SCHEMBL22028085 0.73 GBA1 (0.37) CA2
SCHEMBL20745887 0.73 GBA1 (0.37) CA2
SCHEMBL7921925 0.71 THRB (0.48) CA2
Ammonia Solution, Strong SCHEMBL7928038 0.70 THRB (0.46)
SCHEMBL4395002 0.69 THRB (0.44)
SCHEMBL1565854 0.68 ALDH1A1 (0.52) CA2
SCHEMBL20746294 0.68 GBA1 (0.38) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2287270-B1 Compound containing a fluorinated amide group DU PONT (US) 2013-04-03 EP disclosed
US-8389657-B2 Poly(meth)acrylamides and poly(meth)acrylates containing flourinated amide E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-03-05 US disclosed
EP-2251363-B1 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide DU PONT (US) 2012-12-26 EP disclosed
US-20120264972-A1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-10-18 US disclosed
EP-2054452-B1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE DU PONT (US) 2012-09-19 EP disclosed
US-8178638-B2 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-15 US disclosed
EP-2287270-A2 Composition containing fluorinated amide E. I. du Pont de Nemours and Company (US) 2011-02-23 EP disclosed
EP-2251363-A1 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide E. I. du Pont de Nemours and Company (US) 2010-11-17 EP disclosed
US-20100233419-A1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE E.I.DU PONT DE NEMOURS AND COMPANY (US) 2010-09-16 US disclosed
US-7754838-B2 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-13 US disclosed
EP-2054452-A2 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-06 EP disclosed
WO-2008021153-A2 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-02-21 WO disclosed
US-20080039605-A1 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide E. I. DU PONT DE NEMOURS AND COMPANY 2008-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100233419-A1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE FGB, AFF1, AFF4 CA2 2496/4885
US-20120264972-A1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE AFF1, AFF2, AFF4 CA2 2886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.