SCHEMBL1234939

SCHEMBL1234939

O=C(NCC(O)CNC(=O)C(F)(F)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1233384 0.98 CA2 (0.31)
SCHEMBL1234198 0.78 GBA1 (0.39)
SCHEMBL1233279 0.74
SCHEMBL20745887 0.71 GBA1 (0.37)
SCHEMBL22028085 0.71 GBA1 (0.37)
SCHEMBL4395002 0.70 THRB (0.44)
SCHEMBL1565854 0.69 ALDH1A1 (0.52)
SCHEMBL20746294 0.69 GBA1 (0.38)
SCHEMBL7921925 0.69 THRB (0.48)
SCHEMBL6748824 0.69 THRB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2287270-B1 Compound containing a fluorinated amide group DU PONT (US) 2013-04-03 EP disclosed
US-8389657-B2 Poly(meth)acrylamides and poly(meth)acrylates containing flourinated amide E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-03-05 US disclosed
EP-2251363-B1 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide DU PONT (US) 2012-12-26 EP disclosed
US-20120264972-A1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-10-18 US disclosed
EP-2054452-B1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE DU PONT (US) 2012-09-19 EP disclosed
US-8178638-B2 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-15 US disclosed
EP-2287270-A2 Composition containing fluorinated amide E. I. du Pont de Nemours and Company (US) 2011-02-23 EP disclosed
EP-2251363-A1 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide E. I. du Pont de Nemours and Company (US) 2010-11-17 EP disclosed
US-20100233419-A1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE E.I.DU PONT DE NEMOURS AND COMPANY (US) 2010-09-16 US disclosed
US-7754838-B2 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-13 US disclosed
EP-2054452-A2 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-06 EP disclosed
WO-2008021153-A2 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-02-21 WO disclosed
US-20080039605-A1 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide E. I. DU PONT DE NEMOURS AND COMPANY 2008-02-14 US disclosed