Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409378 | 0.89 | MAPT (0.46) | ACP1MTNR1AMTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL8353285 | 0.86 | ACP1 (0.43) | ACP1MTNR1AMTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL1536561 | 0.86 | ACP1 (0.43) | ACP1MTNR1AMTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL1536661 | 0.86 | ACP1 (0.43) | ACP1MTNR1AMTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL8300158 | 0.82 | NPC1 (0.59) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL8273117 | 0.80 | MTNR1A (0.42) | ACP1MTNR1AMTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL10974850 | 0.77 | ACP1 (0.51) | ACP1MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL8273166 | 0.76 | NPC1 (0.65) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL5068465 | 0.76 | KDM4E (0.45) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8273091 | 0.75 | RAB9A (0.41) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505963-B9 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-09-21 | — | — | EP | disclosed |
| EP-1505963-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-04-20 | — | — | EP | disclosed |