Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12335705 | 0.86 | ACP1 (0.44) | ACP1MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL8351874 | 0.86 | APP (0.48) | ACP1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL1536661 | 0.85 | ACP1 (0.43) | ACP1MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL1536561 | 0.85 | ACP1 (0.43) | ACP1MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL12336056 | 0.83 | HSD17B14 (0.40) | ACP1KDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8272309 | 0.83 | NPC1 (0.57) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL8349901 | 0.82 | MEN1 (0.47) | MTNR1AMTNR1BKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL13409378 | 0.81 | MAPT (0.46) | ACP1MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL8352665 | 0.77 | NPC1 (0.64) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL8353207 | 0.76 | RAB9A (0.40) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099274-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |