SCHEMBL12337353

SCHEMBL12337353

CN1C2=C(C=CCC2)CCc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.36
SLC6A2 P23975 4/20 0.36
ALDH1A1 P00352 4/20 0.36
SLC6A4 P31645 4/20 0.36
ADRA2B P18089 3/20 0.36
ADRA2C P18825 3/20 0.36
HTR2C P28335 3/20 0.36
ADRA1A P35348 3/20 0.36
HRH1 P35367 3/20 0.36
HTR2B P41595 3/20 0.36
KCNH2 Q12809 3/20 0.36
LMNA P02545 3/20 0.36
MAPT P10636 3/20 0.36
SLC22A2 O15244 2/20 0.36
SLC22A1 O15245 2/20 0.36
SLC22A3 O75751 2/20 0.36
CHRM2 P08172 2/20 0.36
CYP2D6 P10635 2/20 0.36
CHRM1 P11229 2/20 0.36
DRD2 P14416 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13568394 0.87 DRD2 (0.34) HTR2ASLC6A2ALDH1A1SLC6A4ADRA2B
SCHEMBL13711335 0.80 L3MBTL1 (0.36) HTR2ASLC6A2ALDH1A1SLC6A4ADRA2B
SCHEMBL25835838 0.74 SETD7 (0.37) HTR2ASLC6A2ALDH1A1SLC6A4ADRA2B
SCHEMBL2604390 0.74 MAOA (0.52) HTR2ASLC6A2ALDH1A1SLC6A4ADRA2B
SCHEMBL1996858 0.73 BRPF1 (0.33) HTR2ASLC6A2ALDH1A1SLC6A4ADRA2B
SCHEMBL31067335 0.73 BRPF1 (0.33) HTR2ASLC6A2ALDH1A1SLC6A4ADRA2B
SCHEMBL13456330 0.71 SRD5A1 (0.34) SRD5A1
SCHEMBL13443065 0.70
SCHEMBL22810601 0.70 MAOA (0.50) SLC6A2ALDH1A1SLC6A4ADRA2BADRA2C
SCHEMBL22879393 0.70 HSD17B3 (0.38) HTR2ASLC6A2ALDH1A1SLC6A4ADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011115378-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-09-22 WO disclosed