Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499691 | 0.76 | SMN1; SMN2 (0.40) | L3MBTL1GAAPOLBNPSR1ALDH1A1 | |
| SCHEMBL11007300 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL11561537 | 0.72 | NR3C2 (0.43) | L3MBTL1GAAPOLBNPSR1ALDH1A1 | |
| SCHEMBL9257555 | 0.71 | MTNR1A (0.38) | GAANPSR1ALDH1A1KMT2ALMNA | |
| SCHEMBL11217085 | 0.70 | LMNA (0.53) | GAANPSR1ALDH1A1NPC1KMT2A | |
| Hydrochloric Acid SCHEMBL11562793 | 0.68 | NPSR1 (0.45) | L3MBTL1GAAPOLBNPSR1ALDH1A1 | |
| SCHEMBL13490300 | 0.67 | L3MBTL1 (0.41) | L3MBTL1GAAPOLBNPSR1ALDH1A1 | |
| SCHEMBL27798753 | 0.67 | ABCG2 (0.58) | GAAALDH1A1NPC1KMT2AHPGD | |
| SCHEMBL12339882 | 0.67 | NPSR1 (0.47) | L3MBTL1GAAPOLBNPSR1ALDH1A1 | |
| SCHEMBL13545197 | 0.64 | HPGD (0.61) | L3MBTL1GAAPOLBALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268814-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-09-18 | — | — | US | disclosed |
| US-20090275558-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275558-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | BDKRB2, BDKRB1, TRPV1 | L3MBTL1 4835/4885GAA 3388/4885POLB 4558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.