SCHEMBL12345737

SCHEMBL12345737

CCCCCC/C=C/CCCCCCCCOCC(COP(=O)(O)OCCC)OCCCCC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ P2RY10 O00398 6/20 0.59
▸ LPAR1 Q92633 6/20 0.56
▸ LPAR3 Q9UBY5 6/20 0.56
▸ GPR34 Q9UPC5 1/20 0.52
▸ LPAR2 Q9HBW0 1/20 0.50
▸ PLA2G2C Q5R387 1/20 0.49
▸ GMNN O75496 1/20 0.49
▸ USP2 O75604 1/20 0.49
▸ LMNA P02545 1/20 0.49
▸ CYP1A2 P05177 1/20 0.49
▸ POLB P06746 1/20 0.49
▸ MAPT P10636 1/20 0.49
▸ CYP2C9 P11712 1/20 0.49
▸ ALOX15 P16050 1/20 0.49
▸ APEX1 P27695 1/20 0.49
▸ CYP2C19 P33261 1/20 0.49
▸ RECQL P46063 1/20 0.49
▸ BLM P54132 1/20 0.49
▸ NPSR1 Q6W5P4 1/20 0.49
▸ HSD17B10 Q99714 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15166530 0.93 LPAR1 (0.64) P2RY10LPAR1LPAR3GPR34LPAR2
SCHEMBL12345666 0.93 LPAR1 (0.64) P2RY10LPAR1LPAR3GPR34LPAR2
SCHEMBL12345674 0.93 LPAR1 (0.64) P2RY10LPAR1LPAR3GPR34LPAR2
SCHEMBL12345684 0.93 LPAR1 (0.64) P2RY10LPAR1LPAR3GPR34LPAR2
SCHEMBL12345698 0.92 LPAR1 (0.61) P2RY10LPAR1LPAR3GPR34LPAR2
SCHEMBL12345686 0.91 LPAR1 (0.64) P2RY10LPAR1LPAR3GPR34LPAR2
SCHEMBL12348984 0.91 P2RY10 (0.53) P2RY10LPAR1LPAR3GPR34LPAR2
SCHEMBL12345705 0.88 LPAR1 (0.61) P2RY10LPAR1LPAR3GPR34LPAR2
SCHEMBL2233966 0.86 PLA2G2C (0.67) P2RY10LPAR1LPAR3GPR34LPAR2
SCHEMBL15166560 0.86 PLA2G2C (0.67) P2RY10LPAR1LPAR3GPR34LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9206206-B2 Oxidized lipid compounds and uses thereof VASCULAR BIOGENICS LTD. (IL) 2015-12-08 — — US disclosed
US-20130203707-A1 Oxidized Lipid Compounds and Uses Thereof VASCULAR BIOGENICS LTD. (IL) 2013-08-08 — — US disclosed
US-20110207703-A1 OXIDIZED LIPID COMPOUNDS AND USES THEREOF VASCULAR BIOGENICS LTD. (IL) 2011-08-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130203707-A1 Oxidized Lipid Compounds and Uses Thereof LPO, GPX4, ALOX15B P2RY10 1977/4885LPAR1 305/4885LPAR3 417/4885
US-20110207703-A1 OXIDIZED LIPID COMPOUNDS AND USES THEREOF LPO, GPX4, ALOX15B P2RY10 1977/4885LPAR1 305/4885LPAR3 417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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