Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 15/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3920685 | 0.77 | FLT3 (0.59) | ALDH1A1MAOBCA2MAOACYP3A4 | |
| SCHEMBL14231743 | 0.77 | MAOB (0.71) | ALDH1A1MAOBCA12CA1CA2 | |
| SCHEMBL170369 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAOBCA12CA1CA2 | |
| SCHEMBL11828796 | 0.76 | MAOB (0.65) | ALDH1A1MAOBCA12CA1CA2 | |
| SCHEMBL23241640 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAOBCA12CA1CA2 | |
| SCHEMBL19794945 | 0.74 | CA2 (0.50) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL15031527 | 0.74 | MAOB (0.55) | ALDH1A1MAOBCA12CA1CA2 | |
| SCHEMBL8548780 | 0.74 | MAOB (0.56) | ALDH1A1MAOBCA12CA1CA2 | |
| SCHEMBL10475847 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAOBCA12CA1CA2 | |
| SCHEMBL13824711 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAOBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858907-B2 | Kinase modulators | RHIZEN PHARMACEUTICALS AG (CH) | 2024-01-02 | — | — | US | disclosed |
| US-11858907-B2 | Kinase modulators | RHIZEN PHARMACEUTICALS AG (CH) | 2024-01-02 | — | — | US | disclosed |
| US-20210401840-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS AG (CH) | 2021-12-30 | — | — | US | disclosed |
| US-11020399-B2 | Intermediates useful in the synthesis of compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2021-06-01 | — | — | US | disclosed |
| US-20200239427-A1 | NOVEL KINASE MODULATORS | RHIZEN PHARMACEUTICALS AG (CH) | 2020-07-30 | — | — | US | disclosed |
| US-10442783-B2 | 2,3-disubstituted chromen-4-one compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2019-10-15 | — | — | US | disclosed |
| US-20190282581-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS AG (CH) | 2019-09-19 | — | — | US | disclosed |
| US-10322130-B2 | Substituted chromenones as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2019-06-18 | — | — | US | disclosed |
| US-20190105324-A9 | SUBSTITUTED CHROMENONES AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS AG (CH) | 2019-04-11 | — | — | US | disclosed |
| US-10220035-B2 | Compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2019-03-05 | — | — | US | disclosed |
| US-20110118257-A1 | NOVEL KINASE MODULATORS | RHIZEN PHARMACEUTICALS SA (CH) | 2011-05-19 | — | — | US | disclosed |
| WO-2011055215-A2 | NOVEL KINASE MODULATORS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-05-12 | — | — | WO | disclosed |
| US-7754403-B2 | asymmetric bishydroxy compound having an excellent charge transporting performance as well as excellent solubility in the solvent and compatibility with the resin where no partial crystals are created at the time of film formation, and electrical properties and durability are both excellent | SHARP KABUSHIKI KAISHA (JP) | 2010-07-13 | — | — | US | disclosed |
| US-7754403-B2 | asymmetric bishydroxy compound having an excellent charge transporting performance as well as excellent solubility in the solvent and compatibility with the resin where no partial crystals are created at the time of film formation, and electrical properties and durability are both excellent | SHARP KABUSHIKI KAISHA (JP) | 2010-07-13 | — | — | US | disclosed |
| US-7625681-B2 | Asymmetric bis-hydroxyenamine compound, electrophotographic photoreceptor and image forming apparatus | SHARP KABUSHIKI KAISHA (JP) | 2009-12-01 | — | — | US | disclosed |
| US-7625681-B2 | Asymmetric bis-hydroxyenamine compound, electrophotographic photoreceptor and image forming apparatus | SHARP KABUSHIKI KAISHA (JP) | 2009-12-01 | — | — | US | disclosed |
| US-7416824-B2 | Organic photoconductive material electrophotographic photoreceptor and image forming apparatus using the same | SHARP KABUSHIKI KAISHA (JP) | 2008-08-26 | — | — | US | disclosed |
| US-7416824-B2 | Organic photoconductive material electrophotographic photoreceptor and image forming apparatus using the same | SHARP KABUSHIKI KAISHA (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20070207395-A1 | Electrophotoconductor and image forming apparatus | SHARP KABUSHIKI KAISHA (JP) | 2007-09-06 | — | — | US | disclosed |
| US-20070207395-A1 | Electrophotoconductor and image forming apparatus | SHARP KABUSHIKI KAISHA (JP) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10442783-B2 | 2,3-disubstituted chromen-4-one compounds as modulators of protein kinases | PIK3CB, PIK3CD, PDPK1 | ALDH1A1 4410/4885MAOB 3695/4885CA12 4793/4885 |
| US-20210401840-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | PRKCA, PRKCH, PRKCB | ALDH1A1 4530/4885MAOB 3694/4885CA12 4845/4885 |
| US-11020399-B2 | Intermediates useful in the synthesis of compounds as modulators of protein kinases | MAP4K2, MAP3K20, MAP3K1 | ALDH1A1 2888/4885MAOB 1477/4885CA12 3351/4885 |
| US-20190105324-A9 | SUBSTITUTED CHROMENONES AS MODULATORS OF PROTEIN KINASES | PRKCA, PRKCH, PRKAR2B | ALDH1A1 4204/4885MAOB 3117/4885CA12 4814/4885 |
| US-10220035-B2 | Compounds as modulators of protein kinases | PRKCA, PRKCH, PRKCE | ALDH1A1 4468/4885MAOB 3665/4885CA12 4799/4885 |
| US-20190282581-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | PRKCA, PRKCH, PRKCB | ALDH1A1 4530/4885MAOB 3694/4885CA12 4845/4885 |
| US-20110118257-A1 | NOVEL KINASE MODULATORS | PRKCA, PRKCH, PRKCB | ALDH1A1 4305/4885MAOB 3933/4885CA12 4816/4885 |
| US-20200239427-A1 | NOVEL KINASE MODULATORS | PRKCA, PRKCH, PRKCB | ALDH1A1 4305/4885MAOB 3933/4885CA12 4816/4885 |
| US-10322130-B2 | Substituted chromenones as modulators of protein kinases | MAP3K1, CSNK1A1, MAP3K2 | ALDH1A1 3618/4885MAOB 2586/4885CA12 4329/4885 |
| US-11858907-B2 | Kinase modulators | RPS6KA1, RPS6KA2, PRKAR2A | ALDH1A1 3748/4885MAOB 3259/4885CA12 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.